Natrixam MR 1.5mg/10mg FC Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Natrixam MR 1.5mg/10mg FC Tablet contains Indapamide 1.5mg (modified release) and Amlodipine 10mg (as amlodipine besilate) and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Natrixam MR 1.5mg/10mg FC Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Swallow Natrixam MR 1.5mg/10mg FC Tablet whole with a glass of water, preferably in the morning, with or without food. Do not crush or chew the tablet, as it is designed to release indapamide gradually. Take it at the same time each day and do not stop treatment suddenly without consulting your doctor, as blood pressure control needs to be maintained continuously.

Dosage

The usual dose of Natrixam MR 1.5mg/10mg FC Tablet is one tablet once daily, generally taken in the morning. Your doctor determines whether this combination and this specific amlodipine dose is appropriate for you based on your blood pressure response and tolerability to the individual components.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or lightheadedness, especially when standing up quickly
  • Headache
  • Muscle cramps or weakness
  • Increased urination
  • Nausea or upset stomach
  • Fatigue or tiredness
  • Low potassium levels (may require monitoring)

Contraindications

  • Known hypersensitivity to indapamide, other sulfonamide-derived medicines, amlodipine, other dihydropyridines, or any ingredient in this product
  • Severe kidney impairment or anuria
  • Severe liver impairment or hepatic encephalopathy
  • Uncorrected low blood potassium levels
  • Severe hypotension, cardiogenic shock, or significant aortic stenosis

Drug / Food Interactions

  • Lithium levels may increase when combined with indapamide, requiring closer monitoring
  • NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
  • Potassium-sparing diuretics, potassium supplements, or ACE inhibitors/ARBs can increase the risk of abnormal blood potassium levels
  • Grapefruit juice may increase amlodipine blood levels and should be limited

Quick Tips

  • Take at the same time each day, preferably in the morning
  • Attend scheduled blood tests to monitor your kidney function and electrolyte (sodium/potassium) levels
  • Rise slowly from sitting or lying down to reduce dizziness
  • Limit grapefruit juice while taking this medicine
  • Do not stop this medicine abruptly without medical advice
  • Monitor your blood pressure regularly as advised by your doctor

Ingredients / Active Ingredients

  • Indapamide 1.5mg (modified release)
  • Amlodipine 10mg (as amlodipine besilate)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandServier
ClassificationPrescription medicine
Ingredients / Active IngredientsIndapamide
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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