Triplixam 10/2.5/10mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Triplixam 10/2.5/10mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Perindopril arginine 10mg, Indapamide 2.5mg and Amlodipine 10mgmg (as amlodipine besylate) as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take the tablet once daily in the morning, before breakfast, swallowed whole with a glass of water.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or lightheadedness, especially when standing up quickly
  • Headache
  • Muscle cramps or weakness
  • Increased urination
  • Nausea or upset stomach
  • Fatigue or tiredness
  • Low potassium levels (may require monitoring)

Contraindications

  • Known hypersensitivity to perindopril or any ACE inhibitor, indapamide or other sulfonamides, amlodipine or other dihydropyridines, or any excipient
  • History of angioedema related to previous ACE inhibitor treatment
  • Pregnancy and breastfeeding
  • Severe kidney impairment or severe liver impairment/hepatic encephalopathy
  • Concurrent use with aliskiren-containing medicines in patients with diabetes or kidney impairment

Drug / Food Interactions

  • Potassium-sparing diuretics, potassium supplements, or salt substitutes may increase blood potassium to dangerous levels when combined with perindopril.
  • NSAIDs (such as ibuprofen) may reduce the blood pressure-lowering effect and increase the risk of kidney problems.
  • Lithium levels may rise when taken with this medicine, requiring closer monitoring.
  • Inform your doctor of all medicines you are taking, including other blood pressure or heart medicines.

Quick Tips

  • Attend all scheduled blood tests to monitor your kidney function and blood potassium/sodium levels.
  • Rise slowly from sitting or lying positions to reduce dizziness, especially when starting treatment.
  • Report a persistent dry cough to your doctor, as this is a known effect of the perindopril component.
  • Do not stop this medicine suddenly without consulting your doctor.

Ingredients / Active Ingredients

  • Perindopril arginine 10mg
  • Indapamide 2.5mg
  • Amlodipine 10mgmg (as amlodipine besylate)

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandServier
ManufacturerServier
ClassificationPrescription medicine
Ingredients / Active IngredientsIndapamide
Pack Size30s
DosageThe usual dose is one 10/2.5/10mgmg tablet taken once daily, preferably in the morning before a meal. Your doctor determines the appropriate strength based on your prior response to the individual medicines.
Shelf LifeRefer to the expiry date printed on the packaging.

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