Pentasa (Mesalazine) 500mg Tablet

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Brand Ferring
Manufacturer Ferring
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Pentasa 500mg Tablet contains Mesalazine 500mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Pentasa 500mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Swallow Pentasa 500mg Tablet whole with a glass of water; do not chew, crush, or break the tablet, as this is designed to release the medicine gradually as it passes through the colon. It can be taken with or without food, spread evenly through the day as directed by your doctor.

Dosage

The dose of Pentasa 500mg Tablet is individualised by the doctor based on the extent and severity of disease, and differs between an active flare and long-term maintenance therapy. Always use exactly the dose and frequency prescribed, and do not stop maintenance treatment without medical advice even during symptom-free periods.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Nausea
  • Abdominal pain or cramps
  • Flatulence (gas)
  • Diarrhea
  • Dizziness
  • Rash or skin reactions
  • Joint pain

Contraindications

  • Known hypersensitivity to mesalazine, other salicylates, or any ingredient in this product
  • Severe kidney impairment
  • Severe liver impairment
  • Active peptic ulcer disease

Drug / Food Interactions

  • Azathioprine or mercaptopurine: combined use may increase the risk of blood-related side effects and needs closer monitoring
  • Warfarin: mesalazine may enhance its blood-thinning effect, requiring closer INR monitoring
  • Other nephrotoxic drugs may increase the risk of kidney-related side effects
  • Lactulose or other agents that lower colonic pH may alter the release of some pH-dependent mesalazine formulations

Quick Tips

  • Use this medicine regularly as prescribed, even during symptom-free periods, to help maintain remission
  • Attend scheduled blood and kidney function tests as advised by your doctor
  • Report unexplained bruising, sore throat, or fever to your doctor promptly
  • Do not chew or crush prolonged-release tablets or granules
  • Seek medical advice if your bowel symptoms suddenly worsen instead of improving

Ingredients / Active Ingredients

  • Mesalazine 500mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandFerring
ManufacturerFerring
ClassificationPrescription medicine
Ingredients / Active IngredientsMesalazine
Pack Size100s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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