Progynova 2mg Tablet

Brand Bayer
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  • FDA Approved
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Progynova 2mg Tablet is a tablet with Estradiol valerate 2mg declared as its active content. It is supplied in pack sizes of 28s x3 and 28s.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Take Progynova 2mg Tablet exactly as prescribed by your doctor, usually one tablet daily at the same time each day, swallowed whole with water; your doctor will advise whether you are on a continuous or cyclic regimen, and if you are also prescribed a progestogen, both medicines should be taken according to the specific schedule given.

Dosage

The typical starting dose is one 2mg tablet daily, though your doctor may adjust this to a lower or higher strength depending on your symptom control and individual response, always aiming to use the lowest effective dose for the shortest duration needed to manage your symptoms.

Storage Instructions

Store Progynova 2mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children.

Side Effects

  • Nausea or vomiting
  • Breast tenderness or swelling
  • Headache or migraine
  • Bloating
  • Mood changes
  • Spotting or breakthrough bleeding
  • Increased risk of blood clots with long-term use

Contraindications

  • Known, past, or suspected breast cancer or other oestrogen-dependent cancer
  • Undiagnosed abnormal vaginal bleeding
  • Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
  • Active or recent arterial disease such as heart attack or stroke
  • Severe liver disease or liver tumours
  • Known or suspected pregnancy

Drug / Food Interactions

  • Enzyme-inducing medicines such as rifampicin, certain anticonvulsants (for example carbamazepine or phenytoin), and St John’s Wort may reduce the effectiveness of Progynova 2mg Tablet
  • Concurrent use with tamoxifen may reduce tamoxifen’s effectiveness and should be discussed with your doctor
  • Anticoagulants such as warfarin may require closer monitoring when started or stopped alongside HRT
  • Grapefruit juice may in some cases increase estradiol blood levels; discuss significant dietary changes with your doctor

Quick Tips

  • Use the lowest effective dose for the shortest duration needed to control your symptoms, as advised by your doctor
  • Attend regular follow-up appointments, including breast checks and mammograms as recommended for your age group
  • Report any new, unusual, or heavy vaginal bleeding to your doctor promptly
  • Do not stop or adjust your dose on your own — speak to your doctor first, especially if you experience new symptoms
  • Inform your doctor of any new medical conditions or medicines started while on Progynova 2mg Tablet

Ingredients / Active Ingredients

  • Estradiol valerate 2mg
  • Lactose monohydrate
  • Standard tablet binders and coating agents

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Progynova 2mg Tablet is generally reserved for women with moderate-to-severe menopausal symptoms who have been assessed by a doctor to have a favourable balance of benefits and risks for hormone replacement therapy. Because HRT carries risks that vary with age, time since menopause, and personal health history, DoctorOnCall’s doctors review each customer individually through an online consultation and recommend appropriate monitoring, including periodic reassessment of ongoing need.

Frequently Asked Questions

Product Specifications

BrandBayer
ClassificationNon-prescription
Ingredients / Active IngredientsOestradiol
Pack Size28s, 28s x3
Shelf LifeProgynova 2mg Tablet is generally stable for up to 3 to 5 years from the date of manufacture when unopened, so always check the expiry date printed on the blister strip or carton before use.

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Important Medical Information

💊 Recommended Dosage:

The typical starting dose is one 2mg tablet daily, though your doctor may adjust this to a lower or higher strength depending on your symptom control and individual response, always aiming to use the lowest effective dose for the shortest duration needed to manage your symptoms.

🛑 Contraindications (Do not use if):
  • Known, past, or suspected breast cancer or other oestrogen-dependent cancer
  • Undiagnosed abnormal vaginal bleeding
  • Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
  • Active or recent arterial disease such as heart attack or stroke
  • Severe liver disease or liver tumours
  • Known or suspected pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Breast tenderness or swelling
  • Headache or migraine
  • Bloating
  • Mood changes
  • Spotting or breakthrough bleeding
  • Increased risk of blood clots with long-term use
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.