Upha Glucoxit 500mg Tablet

Upha Glucoxit 500mg Tablet contains Metformin 500mg, a first-line oral medicine used in the long-term management of type 2 diabetes mellitus. It works by reducing the amount of glucose produced by the liver, decreasing glucose absorption from the gut, and improving the body’s sensitivity to insulin, helping to keep blood sugar levels within a target range as part of an overall diabetes care plan. As a diabetes medication requiring ongoing monitoring, Upha Glucoxit is a prescription-only medicine in Malaysia and Singapore, and requires an online consultation with a doctor via DoctorOnCall before it can be dispensed.

Upha Glucoxit is typically prescribed for adults with type 2 diabetes, either alone or in combination with other diabetes medicines or insulin, and is often used alongside diet and lifestyle changes. A doctor will assess kidney function, overall health, and other medicines being taken before confirming that Upha Glucoxit is a suitable and safe choice, and will schedule regular follow-up to monitor blood sugar control and kidney health.

Metformin belongs to the biguanide class of medicines and lowers blood glucose primarily by reducing hepatic glucose production, decreasing intestinal glucose absorption, and increasing peripheral tissue sensitivity to insulin. Unlike some other diabetes medicines, it does not stimulate the pancreas to release more insulin, so it carries a low risk of causing low blood sugar when used alone.

Take Upha Glucoxit exactly as prescribed by your doctor, typically with or immediately after meals to reduce stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor specifically advises this, and do not change your dose or stop taking it without consulting your doctor first.

Dosage is individualised by the prescribing doctor based on blood sugar control, kidney function, and response to treatment, usually starting at a low dose and gradually increased to reduce gastrointestinal side effects. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should never be self-adjusted or shared with another person.

Upha Glucoxit 500mg Tablet is generally stable for up to 36 months from the date of manufacture when stored correctly and left unopened. Always check the expiry date printed on the blister strip or carton before use and do not use expired tablets.

Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep tablets in their original packaging until ready for use, and keep out of reach of children.

• Severe kidney impairment or significantly reduced kidney function
• Acute or unstable conditions that may affect kidney function, such as severe dehydration or shock
• Known hypersensitivity to metformin
• Severe liver disease
• Conditions causing tissue hypoxia, such as severe heart or respiratory failure
• Should be temporarily stopped before procedures involving iodinated contrast dye, as advised by a doctor

• Alcohol should be avoided or limited, as it increases the risk of lactic acidosis and low blood sugar
• Certain diuretics, corticosteroids, and other medicines that raise blood sugar may reduce metformin’s effectiveness
• Iodinated contrast media used in some imaging procedures may temporarily affect kidney function and increase lactic acidosis risk
• Other diabetes medicines or insulin may increase the risk of low blood sugar when combined
• Certain medicines that affect kidney elimination, such as some antibiotics, may alter metformin levels in the body

• Take this medicine exactly as prescribed and attend all scheduled follow-up appointments for blood sugar and kidney function monitoring
• Take with food to reduce stomach upset, especially when starting treatment
• Inform your doctor before any surgery, contrast dye imaging scan, or if you become severely unwell or dehydrated
• Watch for signs of lactic acidosis such as unusual muscle pain, difficulty breathing, or severe tiredness, and seek urgent medical attention if these occur
• Continue diet and lifestyle measures recommended by your doctor alongside this medicine for best blood sugar control

Metformin remains one of the most established and widely prescribed first-line treatments for type 2 diabetes worldwide, valued for its effectiveness and low risk of causing hypoglycaemia when used alone. Because ongoing kidney function monitoring and periodic review of blood sugar control are essential, Upha Glucoxit is dispensed by DoctorOnCall only after a doctor’s assessment, with regular follow-up recommended throughout treatment for patients in Malaysia and Singapore.