Jardiance Duo 12.5mg/1000mgTablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Jardiance Duo 12.5mg/1000mgTablet is a prescription-only medicine (POM) presented as a tablet, with Empagliflozin 12.5mg and Metformin Hydrochloride 1000mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Jardiance Duo 12.5mg/1000mgTablet with meals, usually twice daily as directed by your doctor, to reduce stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it. Drink adequate fluids during the day, and continue following your prescribed diet and exercise plan alongside this medicine.

Dosage

The dose of Jardiance Duo 12.5mg/1000mgTablet is individualised by your doctor based on your current metformin dose and blood sugar control, and is generally taken twice daily with meals. Your doctor will adjust the dose gradually and monitor your kidney function, as the metformin component requires dose adjustment or avoidance when kidney function is significantly reduced.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to empagliflozin, metformin, or any ingredient in this product
  • Severe kidney impairment or acute kidney injury
  • Acute conditions that may alter kidney function or cause tissue hypoxia (e.g. dehydration, severe infection, shock, acute heart failure)
  • Metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment

Drug / Food Interactions

  • Iodinated contrast media used in some X-ray/CT scans may temporarily increase the risk of kidney problems – metformin may need to be paused around the procedure
  • Alcohol may increase the risk of lactic acidosis and low blood sugar
  • Diuretics may increase the risk of dehydration and volume depletion when combined with empagliflozin
  • Other anti-diabetic medicines (e.g. sulfonylureas, insulin) may increase the risk of low blood sugar (hypoglycaemia)

Quick Tips

  • Take with meals to reduce stomach upset
  • Drink enough water each day to stay well hydrated
  • Practise good genital hygiene to reduce the risk of yeast infections
  • Tell your doctor if you are having surgery, a contrast X-ray/CT scan, or become seriously unwell, as this medicine may need to be temporarily stopped

Ingredients / Active Ingredients

  • Empagliflozin 12.5mg
  • Metformin Hydrochloride 1000mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandBoehringer Ingelheim
ManufacturerBoehringer Ingelheim
ClassificationPrescription medicine
Ingredients / Active IngredientsMetformin
Pack Size10s, 60s, 60s x3
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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Important Medical Information

💊 Recommended Dosage:

The dose of Jardiance Duo 12.5mg/1000mgTablet is individualised by your doctor based on your current metformin dose and blood sugar control, and is generally taken twice daily with meals. Your doctor will adjust the dose gradually and monitor your kidney function, as the metformin component requires dose adjustment or avoidance when kidney function is significantly reduced.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to empagliflozin, metformin, or any ingredient in this product
  • Severe kidney impairment or acute kidney injury
  • Acute conditions that may alter kidney function or cause tissue hypoxia (e.g. dehydration, severe infection, shock, acute heart failure)
  • Metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.