Coversyl Plus 5/1.25mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Coversyl Plus 5/1.25mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Perindopril arginine 5mg and Indapamide 1.25mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Coversyl Plus 5/1.25mg Tablet once daily in the morning, before breakfast, as food may reduce absorption. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.

Dosage

Coversyl Plus 5/1.25mg Tablet is usually taken as one tablet once daily in the morning. Your doctor will determine the appropriate strength for you based on your blood pressure response and whether you have previously been controlled on perindopril or indapamide alone. Always take this medicine exactly as prescribed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or lightheadedness, especially when standing up quickly
  • Headache
  • Muscle cramps or weakness
  • Increased urination
  • Nausea or upset stomach
  • Fatigue or tiredness
  • Low potassium levels (may require monitoring)

Contraindications

  • Known hypersensitivity to perindopril, indapamide, other sulfonamide-derived medicines, or any other ACE inhibitor
  • Previous history of angioedema related to ACE inhibitor use
  • Severe kidney impairment or severe liver impairment (including hepatic encephalopathy)
  • Low blood potassium levels that have not been corrected
  • Pregnancy and breastfeeding

Drug / Food Interactions

  • Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
  • Lithium levels may rise significantly with this combination, increasing the risk of lithium toxicity
  • NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
  • Medicines that can lower blood potassium or prolong the QT interval increase the risk of serious heart rhythm problems when combined with indapamide

Quick Tips

  • Take at the same time each morning, before breakfast, to build a consistent routine
  • Rise slowly from sitting or lying down to reduce dizziness, especially when starting treatment
  • Attend scheduled blood tests to monitor your kidney function and blood salt (electrolyte) levels
  • Report a persistent dry cough or muscle cramps to your doctor

Ingredients / Active Ingredients

  • Perindopril arginine 5mg
  • Indapamide 1.25mg

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandServier
ClassificationPrescription medicine
Ingredients / Active IngredientsIndapamide
Pack Size30s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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