Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Diamide 2.5mg/500mg Tablet contains Glibenclamide 2.5mg and is presented as a tablet. It is supplied in a pack size of 10s.
It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.
You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.
Directions for Use
Take Diamide 2.5mg/500mg Tablet exactly as prescribed, usually with or immediately after meals to reduce stomach upset and the risk of low blood sugar; swallow with a full glass of water; do not crush or chew unless advised.
Storage Instructions
Store below 30°C, in a dry place away from moisture and direct sunlight; keep out of reach of children.
Side Effects
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Contraindications
Known hypersensitivity to glibenclamide, metformin, or other sulfonylureas/biguanides
Type 1 diabetes or diabetic ketoacidosis
Severe renal or hepatic impairment
Conditions predisposing to lactic acidosis (e.g. severe dehydration, severe infection, heart or respiratory failure)
Pregnancy and breastfeeding unless directed by a doctor
Drug / Food Interactions
Alcohol may increase the risk of lactic acidosis and hypoglycaemia
Iodinated contrast media used in imaging studies may require temporary discontinuation of metformin
NSAIDs, ACE inhibitors, and certain diuretics may affect kidney function and increase risk
Other antidiabetic drugs or insulin may increase the risk of hypoglycaemia when combined
Quick Tips
Take with meals to reduce gastrointestinal side effects
Do not skip meals after taking this medicine
Inform your doctor before any procedure involving contrast dye/imaging
Have regular kidney function and HbA1c monitoring as advised
Recognise and treat hypoglycaemia symptoms promptly (sweating, tremors, confusion)
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally Safe
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Diamide 2.5mg/500mg Tablet requires regular medical follow-up to monitor kidney function, blood glucose control, and for signs of rare but serious side effects such as lactic acidosis. Doctors typically review kidney function before starting and periodically during treatment. Do not stop or adjust this medicine without consulting your doctor, as this may cause blood sugar levels to become unstable.
Frequently Asked Questions
No. Diamide 2.5mg/500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Diamide 2.5mg/500mg Tablet is a tablet containing Glibenclamide 2.5mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 10s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store below 30°C, in a dry place away from moisture and direct sunlight; keep out of reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Dosage is individualized by the prescribing doctor based on blood glucose response, generally starting low and titrated gradually; do not exceed the maximum dose advised by your doctor.
Shelf Life
Typically 2-3 years from the date of manufacture when unopened; do not use beyond the expiry date printed on the packaging.
What condition or symptom are you treating with this medication?
Please select your condition / symptom before adding to cart.
*Please select the closest match. A pharmacist may call to verify your selection before dispensing.
Important Medical Information
💊 Recommended Dosage:
Dosage is individualized by the prescribing doctor based on blood glucose response, generally starting low and titrated gradually; do not exceed the maximum dose advised by your doctor.
🛑 Contraindications (Do not use if):
Known hypersensitivity to glibenclamide, metformin, or other sulfonylureas/biguanides
Type 1 diabetes or diabetic ketoacidosis
Severe renal or hepatic impairment
Conditions predisposing to lactic acidosis (e.g. severe dehydration, severe infection, heart or respiratory failure)
Pregnancy and breastfeeding unless directed by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.