Diamide 2.5mg/500mg Tablet

Brand Hovid
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Diamide 2.5mg/500mg Tablet contains Glibenclamide 2.5mg and is presented as a tablet. It is supplied in a pack size of 10s.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

Take Diamide 2.5mg/500mg Tablet exactly as prescribed, usually with or immediately after meals to reduce stomach upset and the risk of low blood sugar; swallow with a full glass of water; do not crush or chew unless advised.

Storage Instructions

Store below 30°C, in a dry place away from moisture and direct sunlight; keep out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to glibenclamide, metformin, or other sulfonylureas/biguanides
  • Type 1 diabetes or diabetic ketoacidosis
  • Severe renal or hepatic impairment
  • Conditions predisposing to lactic acidosis (e.g. severe dehydration, severe infection, heart or respiratory failure)
  • Pregnancy and breastfeeding unless directed by a doctor

Drug / Food Interactions

  • Alcohol may increase the risk of lactic acidosis and hypoglycaemia
  • Iodinated contrast media used in imaging studies may require temporary discontinuation of metformin
  • NSAIDs, ACE inhibitors, and certain diuretics may affect kidney function and increase risk
  • Other antidiabetic drugs or insulin may increase the risk of hypoglycaemia when combined

Quick Tips

  • Take with meals to reduce gastrointestinal side effects
  • Do not skip meals after taking this medicine
  • Inform your doctor before any procedure involving contrast dye/imaging
  • Have regular kidney function and HbA1c monitoring as advised
  • Recognise and treat hypoglycaemia symptoms promptly (sweating, tremors, confusion)

Ingredients / Active Ingredients

  • Glibenclamide 2.5mg
  • Metformin Hydrochloride 500mg
  • Standard tablet excipients

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Diamide 2.5mg/500mg Tablet requires regular medical follow-up to monitor kidney function, blood glucose control, and for signs of rare but serious side effects such as lactic acidosis. Doctors typically review kidney function before starting and periodically during treatment. Do not stop or adjust this medicine without consulting your doctor, as this may cause blood sugar levels to become unstable.

Frequently Asked Questions

Product Specifications

BrandHovid
ClassificationNon-prescription
Ingredients / Active IngredientsMetformin
Pack Size10s
DosageDosage is individualized by the prescribing doctor based on blood glucose response, generally starting low and titrated gradually; do not exceed the maximum dose advised by your doctor.
Shelf LifeTypically 2-3 years from the date of manufacture when unopened; do not use beyond the expiry date printed on the packaging.

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Important Medical Information

💊 Recommended Dosage:

Dosage is individualized by the prescribing doctor based on blood glucose response, generally starting low and titrated gradually; do not exceed the maximum dose advised by your doctor.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to glibenclamide, metformin, or other sulfonylureas/biguanides
  • Type 1 diabetes or diabetic ketoacidosis
  • Severe renal or hepatic impairment
  • Conditions predisposing to lactic acidosis (e.g. severe dehydration, severe infection, heart or respiratory failure)
  • Pregnancy and breastfeeding unless directed by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.