Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Dyfenamic 250mg Capsule contains Mefenamic Acid 250mg (single active ingredient per capsule) and is presented as a capsule. It is supplied in a pack size of 10s.
It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.
You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.
Directions for Use
Take Dyfenamic 250mg Capsule exactly as prescribed by your doctor, generally with or after food and a full glass of water to help protect the stomach lining; swallow the capsule whole without chewing or crushing it, and use the lowest effective dose for the shortest duration necessary to control your symptoms.
Dosage
The typical adult dose prescribed is an initial dose of 500mg (two capsules), followed by 250mg (one capsule) every six hours as needed for pain, usually for a maximum of seven days unless your doctor advises otherwise; a lower dose or different schedule may be prescribed for elderly patients or those with reduced kidney or liver function.
Shelf Life
Dyfenamic 250mg Capsule generally has a shelf life of up to 36 months from the date of manufacture when unopened and stored correctly; always check the expiry date printed on the packaging and do not use the product after this date.
Storage Instructions
Store Dyfenamic 250mg Capsule below 30°C in a dry place, away from direct sunlight and moisture, and keep it out of the reach and sight of children in its original packaging.
Side Effects
Stomach pain or discomfort
Nausea or vomiting
Diarrhea or constipation
Headache
Dizziness
Skin rash
Heartburn or indigestion
Contraindications
Active or history of peptic (stomach or duodenal) ulcer or gastrointestinal bleeding
Known hypersensitivity to mefenamic acid, aspirin, or other NSAIDs, including a history of asthma, bronchospasm, or angioedema triggered by these medicines
Severe kidney or liver impairment
Severe heart failure
Pregnancy, particularly during the third trimester
Active inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis
Drug / Food Interactions
Anticoagulants such as warfarin, which may have an increased bleeding risk when combined with mefenamic acid
Other NSAIDs or aspirin, which increase the risk of gastrointestinal side effects
ACE inhibitors, ARBs, or diuretics, which may have reduced effectiveness and increase the risk of kidney problems
Lithium and methotrexate, as mefenamic acid can raise their blood levels
Corticosteroids and SSRIs, which increase the risk of gastrointestinal bleeding when taken together
Quick Tips
Only use Dyfenamic 250mg Capsule under the guidance of the prescribing doctor, and complete a DoctorOnCall online consultation before ordering
Take with food to reduce the risk of stomach upset
Avoid alcohol while taking this medicine, as it can increase the risk of stomach irritation
Do not use for longer than the prescribed duration without follow-up medical advice
Seek urgent medical attention if you notice black stools, vomiting blood, or severe stomach pain
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Use With Care
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Safe If Prescribed
Use only if prescribed, with possible monitoring of kidney function.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Because mefenamic acid carries a class-wide NSAID risk of gastrointestinal, cardiovascular, and renal side effects, your doctor may recommend periodic monitoring or follow-up, particularly if you use Dyfenamic 250mg Capsule regularly or have other risk factors such as older age, existing kidney disease, or concurrent use of other NSAIDs or blood-thinning medicines.
Frequently Asked Questions
No. Dyfenamic 250mg Capsule is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Dyfenamic 250mg Capsule is a capsule containing Mefenamic Acid 250mg (single active ingredient per capsule). The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 10s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store Dyfenamic 250mg Capsule below 30°C in a dry place, away from direct sunlight and moisture, and keep it out of the reach and sight of children in its original packaging. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
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Important Medical Information
💊 Recommended Dosage:
The typical adult dose prescribed is an initial dose of 500mg (two capsules), followed by 250mg (one capsule) every six hours as needed for pain, usually for a maximum of seven days unless your doctor advises otherwise; a lower dose or different schedule may be prescribed for elderly patients or those with reduced kidney or liver function.
🛑 Contraindications (Do not use if):
Active or history of peptic (stomach or duodenal) ulcer or gastrointestinal bleeding
Known hypersensitivity to mefenamic acid, aspirin, or other NSAIDs, including a history of asthma, bronchospasm, or angioedema triggered by these medicines
Severe kidney or liver impairment
Severe heart failure
Pregnancy, particularly during the third trimester
Active inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Stomach pain or discomfort
Nausea or vomiting
Diarrhea or constipation
Headache
Dizziness
Skin rash
Heartburn or indigestion
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
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IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.