Do I need a prescription to buy Glymet 5/500mg Tablet?

No. Glymet 5/500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Glymet 5/500mg Tablet contain?

Glymet 5/500mg Tablet is a tablet containing Glibenclamide 5mg and Metformin 500mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Glymet 5/500mg Tablet come in?

It is supplied in pack sizes of 14s and 56s. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Glymet 5/500mg Tablet is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Glymet 5/500mg Tablet?

Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Glymet 5/500mg Tablet before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

What should I do if I notice side effects after using Glymet 5/500mg Tablet?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Glymet 5/500mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Glymet 5/500mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Glymet 5/500mg Tablet | glibenclamide metformin | type 2 diabetes combination tablet | DoctorOnCall Malaysia

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Glymet 5/500mg Tablet

Brand Orient Europharma

Manufacturer Orient Europharma

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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated: October 31, 2026

Overview

Glymet 5/500mg Tablet is supplied as a tablet, with Glibenclamide 5mg and Metformin 500mg. It is supplied in pack sizes of 14s and 56s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Take Glymet 5/500mg Tablet exactly as prescribed by your doctor, usually with meals to help reduce stomach upset and to align dosing with food intake, which is important given the hypoglycaemia risk associated with glibenclamide. Swallow the tablet with a glass of water. Do not skip meals after taking this medicine, and do not change your dose without consulting your doctor.

Dosage

The dose of Glymet 5/500mg Tablet is individualised by the prescribing doctor based on blood glucose control, kidney and liver function, and response to treatment, and is typically started at a low dose and adjusted gradually. This medicine requires a valid doctor’s prescription; never start, stop, or adjust the dose without medical advice, as incorrect dosing can lead to hypoglycaemia (from glibenclamide) or other complications.

Shelf Life

Glymet 5/500mg Tablet is generally stable for the shelf life stated on the packaging when stored correctly and unopened. Always check the expiry date printed on the carton or blister strip before use, and do not use the tablets after this date.

Storage Instructions

Store Glymet 5/500mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging. Keep out of reach and sight of children. Do not store in the bathroom or near a sink where humidity is high.

Side Effects

Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)

Contraindications

Known hypersensitivity to glibenclamide, metformin, or other sulfonylureas/biguanides
Type 1 diabetes or diabetic ketoacidosis
Severe kidney or liver impairment
Conditions with risk of tissue hypoxia, such as severe heart failure, shock, or recent heart attack
Porphyria
Planned use of iodinated contrast media for imaging without temporary treatment interruption

Drug / Food Interactions

Other antidiabetic medicines, insulin, or alcohol can increase the risk of hypoglycaemia when combined with Glymet
Certain medicines such as beta-blockers may mask the warning signs of hypoglycaemia
Iodinated contrast agents may increase the risk of lactic acidosis and kidney impairment
Corticosteroids and some diuretics may raise blood glucose and reduce the medicine’s effectiveness
Inform your doctor or pharmacist of all other medicines, supplements, and herbal products you are taking

Quick Tips

Take with meals and do not skip meals after dosing, to reduce the risk of hypoglycaemia
Carry a fast-acting sugar source in case of low blood glucose symptoms such as sweating, shakiness, or confusion
Attend regular follow-up appointments to monitor blood glucose, kidney, and liver function
Inform your doctor before any contrast imaging (such as a CT scan) or surgery
Limit alcohol intake while on this medicine
Do not double the dose if you miss one — take the next dose at the usual time

Ingredients / Active Ingredients

Metformin

Glibenclamide 5mg (active ingredient)
Metformin 500mg (active ingredient)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Glymet 5/500mg Tablet combines two antidiabetic agents in a single tablet and requires careful, ongoing medical supervision because of the added hypoglycaemia risk from glibenclamide alongside the metabolic considerations of metformin. Patients should not adjust their treatment without medical guidance and should always consult their doctor or a DoctorOnCall pharmacist with any concerns about their diabetes management.