Jardiance Duo 5mg/500mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Jardiance Duo 5mg/500mg Tablet contains Empagliflozin 5mg and Metformin hydrochloride 500mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Jardiance Duo 5mg/500mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Jardiance Duo 5mg/500mg Tablet with meals to reduce the stomach upset that metformin can cause, swallowing the tablet whole without crushing or chewing it. Maintain adequate fluid intake, particularly during illness, hot weather, or reduced food/fluid intake, since dehydration can affect kidney function and increase the risk of side effects from both components.

Dosage

Jardiance Duo 5mg/500mg Tablet is usually taken once or twice daily depending on the specific strength prescribed, with your doctor selecting the combination and frequency based on your current empagliflozin and metformin doses, blood glucose control, and kidney function. Your doctor will individualise and periodically review your dose, including checking kidney function before and during treatment.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to empagliflozin, metformin, or any ingredient in this product
  • Severe kidney impairment or acute kidney injury
  • Diabetic ketoacidosis or a history of it
  • Acute or chronic metabolic acidosis
  • Conditions predisposing to tissue hypoxia (e.g. severe heart failure, respiratory failure, recent heart attack) due to lactic acidosis risk with metformin

Drug / Food Interactions

  • Diuretics may increase the risk of dehydration and low blood pressure when combined with empagliflozin
  • Iodinated contrast media used in imaging studies require metformin to be temporarily withheld due to acute kidney injury and lactic acidosis risk
  • Alcohol increases the risk of lactic acidosis with metformin and should be limited
  • Other glucose-lowering medicines (e.g. sulfonylureas, insulin) may increase the risk of low blood sugar (hypoglycaemia) when combined

Quick Tips

  • Take with food to reduce stomach upset from the metformin component
  • Maintain good hydration, especially in hot weather, during illness, or if you are eating/drinking less than usual
  • Practise good genital hygiene and seek prompt treatment for any signs of a genital or urinary infection
  • Inform your doctor before any surgery, contrast imaging scan, or major illness, as this medicine may need to be temporarily stopped
  • Monitor your blood glucose as advised and know the symptoms of both high and low blood sugar

Ingredients / Active Ingredients

  • Empagliflozin 5mg
  • Metformin hydrochloride 500mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandBoehringer Ingelheim
ClassificationPrescription medicine
Ingredients / Active IngredientsMetformin
Pack Size60s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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Important Medical Information

💊 Recommended Dosage:

Jardiance Duo 5mg/500mg Tablet is usually taken once or twice daily depending on the specific strength prescribed, with your doctor selecting the combination and frequency based on your current empagliflozin and metformin doses, blood glucose control, and kidney function. Your doctor will individualise and periodically review your dose, including checking kidney function before and during treatment.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to empagliflozin, metformin, or any ingredient in this product
  • Severe kidney impairment or acute kidney injury
  • Diabetic ketoacidosis or a history of it
  • Acute or chronic metabolic acidosis
  • Conditions predisposing to tissue hypoxia (e.g. severe heart failure, respiratory failure, recent heart attack) due to lactic acidosis risk with metformin
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.