Pharmaniaga Glumet DC 500mg Tablet

Pharmaniaga Glumet DC 500mg Tablet is a standard-strength, immediate-release metformin hydrochloride tablet used in the treatment of type 2 diabetes mellitus in adults. At 500mg, it is the lowest strength in the Glumet range and is commonly the tablet doctors start with when first prescribing metformin, allowing the dose to be titrated upward gradually as the body adjusts. Glumet DC 500mg Tablet is a prescription-only medicine in Malaysia and must be used under a doctor’s supervision as part of a broader diabetes management plan that includes healthy eating and regular physical activity.

As an immediate-release tablet, Glumet DC 500mg is typically taken two to three times a day with meals, and because of its lower strength per tablet it is often the preferred starting point for patients who are more sensitive to metformin’s gastrointestinal side effects, or who need finer dose adjustments than a higher-strength tablet allows. It is manufactured by Pharmaniaga and is not intended for type 1 diabetes or diabetic ketoacidosis. Through DoctorOnCall, patients with a valid prescription, or those who complete an online medical consultation, can have Glumet DC 500mg Tablet reviewed, dispensed, and delivered by a registered pharmacist in Malaysia and Singapore.

Metformin 500mg lowers blood glucose mainly by reducing the liver’s output of glucose, slowing intestinal glucose absorption, and improving how sensitive muscle and fat tissue are to insulin, so glucose is cleared from the bloodstream more effectively. It does not push the pancreas to release more insulin, so the risk of hypoglycaemia is low when it is used on its own. Because Glumet DC 500mg is a lower, immediate-release strength, it gives doctors a flexible way to start metformin therapy gently and step the dose up in small increments as the body adapts and side effects are monitored.

Take Glumet DC 500mg Tablet exactly as prescribed by your doctor, generally two to three times a day, with or immediately after meals to reduce the chance of stomach upset. Swallow each tablet whole with a glass of water. If your doctor has started you on a lower frequency to begin with, follow the schedule given and do not increase the dose or frequency yourself, even if you feel your blood sugar is not well controlled — dose changes should always be reviewed by your doctor.

Glumet DC 500mg Tablet is often used as the starting dose when metformin therapy is first prescribed, typically once or twice daily initially, with the dose and frequency increased gradually over one to two weeks or longer as directed by your doctor, based on your blood glucose response and tolerance. The dose is individualised according to kidney function, blood glucose control, and how well you tolerate the medicine, and must never be adjusted without medical advice. Regular monitoring of blood glucose, HbA1c, and kidney function is required. If a dose is missed, take it as soon as remembered unless it is almost time for the next dose; never double the dose.

Please refer to the expiry date printed on the blister strip or carton, and do not use Glumet DC 500mg Tablet beyond this date.

Store Glumet DC 500mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the reach of children. Keep tablets in their original blister packaging until ready for use.

• Known hypersensitivity to metformin or any ingredient in the tablet.
• Severe kidney impairment.
• Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
• Severe liver impairment.
• Conditions causing tissue hypoxia, such as recent heart attack, severe heart failure, or shock.
• Acute conditions with risk of altered kidney function, such as severe dehydration or serious infection.

• Iodinated contrast media used in imaging studies may increase the risk of lactic acidosis; metformin may need to be paused before and after such procedures.
• Alcohol increases the risk of lactic acidosis and low blood sugar when combined with metformin.
• Some diuretics, corticosteroids, and blood pressure medicines may affect blood glucose control.
• Insulin and sulfonylureas may increase the risk of hypoglycaemia when combined with metformin.
• Cimetidine may increase metformin blood levels.

• Take each dose with or right after a meal to reduce stomach upset.
• Follow the step-up dosing schedule your doctor gives you — do not rush to a higher dose.
• Keep up with scheduled blood tests for kidney function and vitamin B12.
• Continue your prescribed diet and exercise plan alongside this medicine.
• Never double a dose if one is missed.
• Tell your doctor before any surgery or contrast imaging scan.

Precautions: Glumet DC 500mg Tablet should be used with caution in elderly patients, people with reduced kidney function, and those who consume alcohol regularly, as these factors raise the risk of lactic acidosis. It is not recommended in pregnancy or breastfeeding unless specifically advised by a doctor and is not intended for children.

When to See a Doctor or Pharmacist: Seek prompt medical attention if you develop persistent vomiting, severe abdominal pain, difficulty breathing, unusual muscle pain, or unusually low body temperature, as these may indicate lactic acidosis. Contact DoctorOnCall’s pharmacist team if you have questions about starting metformin, dose titration, or side effects.