Pharmaniaga Glumet Forte 850mg Tablet

Pharmaniaga Glumet Forte 850mg Tablet is an immediate-release metformin hydrochloride tablet at a higher 850mg strength, used in the treatment of type 2 diabetes mellitus in adults. It belongs to the biguanide class of oral antidiabetic medicines and is commonly prescribed when a patient’s blood glucose control needs more than a lower-strength metformin tablet can provide, or as part of a stepped-up dose regimen decided by the treating doctor. Glumet Forte 850mg Tablet is a prescription-only medicine in Malaysia and must be used under a doctor’s supervision alongside a suitable diet and exercise programme.

Unlike an extended-release (XR) formulation, Glumet Forte 850mg is an immediate-release tablet, meaning the active ingredient is released and absorbed relatively quickly after each dose; it is therefore usually taken two to three times a day with meals rather than once daily. It is manufactured by Pharmaniaga and is not suitable for type 1 diabetes or diabetic ketoacidosis. Through DoctorOnCall, patients with a valid prescription, or those who complete an online medical consultation, can have Glumet Forte 850mg Tablet reviewed, dispensed, and delivered by a registered pharmacist in Malaysia and Singapore.

Metformin 850mg works by reducing the amount of glucose the liver releases into the bloodstream, reducing intestinal glucose absorption, and increasing how well muscle and fat cells respond to the body’s own insulin, so glucose is taken up and used more efficiently. It does not stimulate additional insulin release from the pancreas, which is why it carries a low risk of hypoglycaemia when used alone. Because Glumet Forte 850mg is an immediate-release tablet, each dose produces a relatively quick rise and fall in metformin blood levels, so dosing two to three times daily with meals helps maintain steady glucose-lowering effect throughout the day.

Take Glumet Forte 850mg Tablet exactly as prescribed by your doctor, generally two to three times a day, with or right after meals to reduce stomach upset. Swallow each tablet whole with a glass of water; it may be halved along the score line only if your doctor or pharmacist has specifically advised this. Space your doses evenly through the day as instructed, and do not exceed the prescribed frequency, even if your blood glucose readings look good.

Your doctor will determine the correct dose of Glumet Forte 850mg Tablet based on your blood glucose levels, kidney function, and how you respond to treatment; the dose is often started low and increased gradually over several weeks to reduce gastrointestinal side effects. Because this is an 850mg strength tablet, your doctor will decide how many times a day it should be taken to reach the total daily dose that suits you, and this should never be adjusted without medical advice. Regular blood tests to check kidney function and blood glucose control are needed during treatment. If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose — never double up.

Please refer to the expiry date printed on the blister strip or carton, and do not use Glumet Forte 850mg Tablet beyond this date.

Store Glumet Forte 850mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the reach of children. Keep tablets in their original blister packaging until ready for use.

• Known hypersensitivity to metformin or any ingredient in the tablet.
• Severe kidney impairment.
• Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
• Severe liver impairment.
• Conditions causing tissue hypoxia, such as recent heart attack, severe heart failure, or shock.
• Acute conditions with risk of altered kidney function, such as severe dehydration, serious infection, or shock.

• Iodinated contrast media used in imaging studies may increase the risk of lactic acidosis; metformin may need to be temporarily stopped before and after such procedures.
• Alcohol increases the risk of lactic acidosis and low blood sugar when combined with metformin.
• Some diuretics, corticosteroids, and blood pressure medicines can raise blood glucose levels.
• Insulin and sulfonylureas may increase the risk of hypoglycaemia when taken together with metformin.
• Cimetidine may increase metformin blood levels.

• Take each dose with or right after a meal to reduce stomach upset.
• Space doses evenly through the day as instructed by your doctor.
• Never double a dose if one is missed.
• Keep up with scheduled blood tests for kidney function and vitamin B12.
• Pair this medicine with your prescribed diet and exercise plan for best results.
• Tell your doctor before any surgery or contrast imaging scan.

Precautions: Glumet Forte 850mg Tablet should be used cautiously in elderly patients, people with reduced kidney function, and those who drink alcohol regularly, as these increase the risk of lactic acidosis. It is not recommended in pregnancy or breastfeeding unless specifically advised by a doctor and is not intended for children.

When to See a Doctor or Pharmacist: Seek urgent medical care if you develop persistent vomiting, severe stomach pain, difficulty breathing, unusual muscle pain, or unusually low body temperature, as these can be signs of lactic acidosis. Contact DoctorOnCall’s pharmacist team with any questions about dosing frequency, missed doses, or side effects.