Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Proglutrol 500mg Tablet contains Metformin hydrochloride 500mg and is presented as a tablet. It is supplied in a pack size of 100s.
It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.
You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.
Directions for Use
Take Proglutrol 500mg Tablet exactly as prescribed by your doctor, generally with or immediately after meals to reduce stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor advises otherwise. Continue taking it regularly even if you feel well, as diabetes often has no obvious symptoms, and do not stop treatment without consulting your doctor.
Dosage
The starting dose and titration schedule are determined by your doctor based on your blood sugar levels, kidney function, and response to treatment, typically beginning at a low dose that is gradually increased to reduce gastrointestinal side effects. Doses are usually divided across two or three meals per day, and the maximum dose should not exceed the limit set by your doctor.
Storage Instructions
Store Proglutrol 500mg Tablet below 30°C in a dry place, away from direct sunlight and moisture, and keep it out of the reach of children.
Side Effects
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Contraindications
Severe kidney impairment or acute kidney injury
Metabolic acidosis, including diabetic ketoacidosis
Severe liver disease
Conditions causing tissue hypoxia, such as severe heart failure or respiratory failure
Acute conditions with risk of altered kidney function, such as severe dehydration or serious infection
Known hypersensitivity to metformin
Drug / Food Interactions
Iodinated contrast media used in imaging procedures may require temporary discontinuation of metformin
Alcohol increases the risk of lactic acidosis and should be limited
Certain diuretics, corticosteroids, and other medicines that affect blood sugar or kidney function may require dose adjustment
Concurrent use with other glucose-lowering medicines or insulin may increase the risk of hypoglycaemia
Cimetidine may increase metformin blood levels
Quick Tips
Take Proglutrol 500mg Tablet with meals to minimise stomach upset
Monitor your blood sugar as advised by your doctor and keep a record for follow-up visits
Inform your doctor before any procedure involving contrast dye or planned surgery
Maintain a healthy diet and regular physical activity alongside your medication
Do not stop treatment abruptly without consulting your doctor, even if you feel well
Seek urgent medical attention if you experience unusual muscle pain, breathing difficulty, or severe tiredness, which may signal lactic acidosis
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally Safe
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Because metformin is cleared through the kidneys, your doctor at DoctorOnCall will consider your kidney function, age, and any other medical conditions before prescribing Proglutrol 500mg Tablet, and periodic monitoring of kidney function and vitamin B12 levels may be recommended during long-term use.
Frequently Asked Questions
No. Proglutrol 500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Proglutrol 500mg Tablet is a tablet containing Metformin hydrochloride 500mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 100s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store Proglutrol 500mg Tablet below 30°C in a dry place, away from direct sunlight and moisture, and keep it out of the reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Product Specifications
Classification
Non-prescription
Ingredients / Active Ingredients
Metformin
Pack Size
100s
Shelf Life
Proglutrol 500mg Tablet remains stable until the expiry date printed on the packaging when stored correctly and left unopened. Do not use the tablets after this date has passed.
What condition or symptom are you treating with this medication?
Please select your condition / symptom before adding to cart.
*Please select the closest match. A pharmacist may call to verify your selection before dispensing.
Important Medical Information
💊 Recommended Dosage:
The starting dose and titration schedule are determined by your doctor based on your blood sugar levels, kidney function, and response to treatment, typically beginning at a low dose that is gradually increased to reduce gastrointestinal side effects. Doses are usually divided across two or three meals per day, and the maximum dose should not exceed the limit set by your doctor.
🛑 Contraindications (Do not use if):
Severe kidney impairment or acute kidney injury
Metabolic acidosis, including diabetic ketoacidosis
Severe liver disease
Conditions causing tissue hypoxia, such as severe heart failure or respiratory failure
Acute conditions with risk of altered kidney function, such as severe dehydration or serious infection
Known hypersensitivity to metformin
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.