Diamide 5mg/500mg Tablet

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Overview

Diamide 5mg/500mg Tablet is supplied as a tablet, with Glibenclamide 5mg. It is supplied in pack sizes of 10s and 120s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Diamide tablets should be taken exactly as prescribed by your doctor, typically with meals to reduce the risk of stomach upset and to help align the medicine’s effect with rising blood glucose after eating. It should not be skipped, doubled up, or stopped without medical advice, and blood glucose should be monitored as advised by your healthcare provider.

Dosage

The dose of Diamide is individualised based on blood glucose control, kidney function, and response to treatment, and must be determined and adjusted by your doctor rather than self-adjusted. Doses are usually started low and increased gradually, and it is important to attend regular follow-up appointments so your doctor can review your HbA1c and blood glucose readings and adjust treatment as needed.

Shelf Life

Diamide tablets remain stable until the expiry date printed on the blister pack or carton when stored correctly and unopened; the expiry date should always be checked before use.

Storage Instructions

Store below 30°C in a dry place away from direct sunlight and moisture, keeping tablets in their original packaging until ready to use. Keep out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to glibenclamide, metformin, other sulfonylureas, or any ingredient in the tablet
  • Type 1 diabetes or diabetic ketoacidosis
  • Significant kidney impairment
  • Severe liver disease
  • Conditions with a risk of tissue hypoxia, such as recent heart attack, severe heart failure, or severe respiratory failure
  • Acute or unstable conditions that may affect kidney function, such as severe dehydration, serious infection, or shock
  • Use of iodinated contrast media requiring temporary discontinuation, as advised by your doctor

Drug / Food Interactions

  • Alcohol may increase the risk of hypoglycaemia and, rarely, lactic acidosis when combined with metformin
  • Other glucose-lowering medicines, including insulin, may increase the risk of hypoglycaemia if not carefully coordinated
  • Corticosteroids, thiazide diuretics, and certain other medicines may raise blood glucose and reduce the effectiveness of Diamide
  • Beta-blockers may mask the warning signs of hypoglycaemia, such as a fast heartbeat
  • Certain antibiotics and other medicines can alter glibenclamide levels; always inform your doctor of all medicines you take

Quick Tips

  • Take Diamide with meals as prescribed to reduce stomach upset and hypoglycaemia risk
  • Always carry a fast-acting source of sugar in case of low blood sugar symptoms such as shakiness, sweating, or confusion
  • Monitor your blood glucose as advised and keep a record to share with your doctor
  • Do not skip meals while taking this medicine
  • Attend regular check-ups to monitor kidney function and overall diabetes control
  • Seek urgent medical attention if you experience unusual muscle pain, difficulty breathing, or severe tiredness, which could indicate a rare but serious side effect

Frequently Asked Questions

Do I need a prescription to buy Diamide 5mg/500mg Tablet?

No. Diamide 5mg/500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Diamide 5mg/500mg Tablet contain?

Diamide 5mg/500mg Tablet is a tablet containing Glibenclamide 5mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Diamide 5mg/500mg Tablet come in?

It is supplied in pack sizes of 10s and 120s. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Diamide 5mg/500mg Tablet is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Diamide 5mg/500mg Tablet?

Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Diamide 5mg/500mg Tablet before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

How should I store Diamide 5mg/500mg Tablet?

Store below 30°C in a dry place away from direct sunlight and moisture, keeping tablets in their original packaging until ready to use. Keep out of reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects after using Diamide 5mg/500mg Tablet?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Diamide 5mg/500mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Diamide 5mg/500mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Glibenclamide 5mg
  • Metformin Hydrochloride 500mg
  • Microcrystalline cellulose
  • Povidone
  • Magnesium stearate
  • Colloidal silicon dioxide

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Diamide is part of a broader diabetes management plan that should also include regular blood glucose monitoring, a balanced diet, physical activity, and periodic laboratory tests such as kidney function and HbA1c, as directed by your doctor. Because it combines two glucose-lowering mechanisms, careful medical supervision is especially important to balance effective blood sugar control against the risk of hypoglycaemia and other side effects.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

The dose of Diamide is individualised based on blood glucose control, kidney function, and response to treatment, and must be determined and adjusted by your doctor rather than self-adjusted. Doses are usually started low and increased gradually, and it is important to attend regular follow-up appointments so your doctor can review your HbA1c and blood glucose readings and adjust treatment as needed.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to glibenclamide, metformin, other sulfonylureas, or any ingredient in the tablet
  • Type 1 diabetes or diabetic ketoacidosis
  • Significant kidney impairment
  • Severe liver disease
  • Conditions with a risk of tissue hypoxia, such as recent heart attack, severe heart failure, or severe respiratory failure
  • Acute or unstable conditions that may affect kidney function, such as severe dehydration, serious infection, or shock
  • Use of iodinated contrast media requiring temporary discontinuation, as advised by your doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.