Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Glucophage 1000mg Tablet is supplied as a tablet, with Metformin Hydrochloride 1000mg. It is supplied in pack sizes of 120s and 15s.
No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.
If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.
Directions for Use
Glucophage 1000mg Tablet should be taken exactly as prescribed, generally with or immediately after a main meal to reduce stomach-related side effects. At this higher strength, doctors commonly split the daily dose across two meals rather than giving it all at once, so patients should follow their specific dosing schedule rather than assuming a single daily dose. Tablets should be swallowed whole with water and not crushed or chewed unless the doctor has specifically advised otherwise.
Dosage
The dose of Glucophage 1000mg Tablet is individualised by the prescribing doctor based on blood glucose control, kidney function, and response to lower Metformin strengths used earlier in treatment. It is typically part of a total daily Metformin dose that is divided across two main meals rather than taken as a single 1000mg dose, and any adjustment should only be made by the doctor after reviewing blood glucose readings and, where relevant, kidney function tests.
Storage Instructions
Store below 30°C in a dry place, protected from direct light and humidity, and keep tablets in their original blister packaging until they are needed. Keep out of the sight and reach of children at all times.
Side Effects
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Contraindications
Known hypersensitivity to metformin
Moderate to severe kidney impairment, as assessed by the prescribing doctor
Acute conditions with risk of altered kidney function, such as severe dehydration, serious infection, or shock
Uncontrolled or decompensated heart failure, or acute or unstable heart failure
Conditions predisposing to tissue hypoxia, such as acute heart attack or severe respiratory failure
Planned use of iodinated contrast dye for imaging, unless timed by the doctor around the procedure
Drug / Food Interactions
Iodinated contrast media used in certain imaging scans — Metformin may need to be temporarily stopped around the procedure on your doctor’s advice
Alcohol — excessive intake increases the risk of lactic acidosis, especially with liver problems or fasting
Certain diuretics, corticosteroids, and other medicines that can affect kidney function or blood glucose control
Other glucose-lowering medicines or insulin — combined use may increase the risk of low blood sugar and requires monitoring
Take with food as directed, as this reduces gastrointestinal side effects
Quick Tips
Take Glucophage 1000mg Tablet exactly at the times and with the meals your doctor has specified, since the dose is often split across the day at this strength
Never double up a missed dose; simply continue with the next scheduled dose
Attend regular follow-ups so kidney function and blood glucose control can be monitored
Inform your doctor before any scan involving contrast dye or before surgery
Watch for unusual muscle pain, breathing difficulty, or severe tiredness, and seek medical attention promptly if these occur
Film-coating agents as used in the branded formulation
Safety Advice
Pregnancy
Use With Care
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally Safe
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Glucophage 1000mg Tablet is typically prescribed once a patient’s Metformin requirement has increased beyond the standard starting strengths, and it is usually part of a broader diabetes management plan that also includes diet, physical activity, and periodic blood tests. Because it is a higher tablet strength, doctors pay particular attention to kidney function before and during treatment, and any online consultation through DoctorOnCall will include a review of these factors before the prescription is confirmed or renewed.
Frequently Asked Questions
No. Glucophage 1000mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Glucophage 1000mg Tablet is a tablet containing Metformin Hydrochloride 1000mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in pack sizes of 120s and 15s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store below 30°C in a dry place, protected from direct light and humidity, and keep tablets in their original blister packaging until they are needed. Keep out of the sight and reach of children at all times. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Glucophage 1000mg Tablet is generally stable until the expiry date printed on the blister or carton when stored under the recommended conditions. Do not use the tablets beyond the printed expiry date.
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Important Medical Information
💊 Recommended Dosage:
The dose of Glucophage 1000mg Tablet is individualised by the prescribing doctor based on blood glucose control, kidney function, and response to lower Metformin strengths used earlier in treatment. It is typically part of a total daily Metformin dose that is divided across two main meals rather than taken as a single 1000mg dose, and any adjustment should only be made by the doctor after reviewing blood glucose readings and, where relevant, kidney function tests.
🛑 Contraindications (Do not use if):
Known hypersensitivity to metformin
Moderate to severe kidney impairment, as assessed by the prescribing doctor
Acute conditions with risk of altered kidney function, such as severe dehydration, serious infection, or shock
Uncontrolled or decompensated heart failure, or acute or unstable heart failure
Conditions predisposing to tissue hypoxia, such as acute heart attack or severe respiratory failure
Planned use of iodinated contrast dye for imaging, unless timed by the doctor around the procedure
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.