Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Glucophage XR 1000mg Tablet is supplied as a tablet, with Metformin Hydrochloride 1000mg. It is supplied in pack sizes of 60s-x3, 10s and 60s.
No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.
If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.
Directions for Use
Glucophage XR 1000mg Tablet is usually taken once daily with the evening meal, exactly as prescribed by the doctor. The tablet must be swallowed whole and never split, crushed, or chewed, as doing so can disrupt the extended-release mechanism and cause the full dose to be released too quickly. It is normal to occasionally notice something resembling the tablet shell in the stool, as the outer matrix is designed to pass through after releasing the active medicine.
Dosage
The dose of Glucophage XR 1000mg Tablet is individualised by the prescribing doctor, typically as part of a gradual increase from a lower XR strength based on blood glucose control and tolerability. Because it is an extended-release formulation, the total daily dose is generally taken as a single dose with the evening meal rather than split across the day, and any change should only be made by the doctor after reviewing blood glucose readings and kidney function.
Storage Instructions
Store below 30°C in a dry place, protected from direct light and humidity, and keep tablets in their original blister packaging until needed. Keep out of the sight and reach of children.
Side Effects
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Contraindications
Known hypersensitivity to metformin
Moderate to severe kidney impairment, as assessed by the prescribing doctor
Acute conditions with risk of altered kidney function, such as severe dehydration, serious infection, or shock
Unstable or acute decompensated heart failure
Conditions predisposing to tissue hypoxia, such as acute heart attack or severe respiratory failure
Planned use of iodinated contrast dye for imaging, unless timed by the doctor around the procedure
Any condition causing significant narrowing of the gastrointestinal tract, which may affect passage of the tablet matrix
Drug / Food Interactions
Iodinated contrast media used in certain imaging scans — Metformin may need to be temporarily stopped around the procedure on your doctor’s advice
Alcohol — excessive intake increases the risk of lactic acidosis, especially with liver problems or fasting
Certain diuretics, corticosteroids, and other medicines that can affect kidney function or blood glucose control
Other glucose-lowering medicines or insulin — combined use may increase the risk of low blood sugar and requires monitoring
Take with the evening meal as directed, as this supports the intended release profile and reduces gastrointestinal side effects
Quick Tips
Swallow Glucophage XR 1000mg Tablet whole; never crush, split, or chew it, as this disrupts the extended-release mechanism
Take it with your evening meal at a consistent time each day
Do not be alarmed if you notice a tablet-like residue in your stool; this is the empty matrix and does not mean the dose was not absorbed
Attend regular follow-ups so kidney function and blood glucose control can be monitored
Inform your doctor before any scan involving contrast dye or before surgery
Hypromellose and other polymers forming the extended-release matrix
Magnesium stearate as a lubricant
Film-coating agents as used in the branded formulation
Safety Advice
Pregnancy
Use With Care
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally Safe
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Glucophage XR 1000mg Tablet offers a once-daily dosing option at the highest standard Metformin strength, which many patients find more convenient than splitting an equivalent immediate-release dose across multiple meals. As with all Metformin-containing medicines, kidney function is assessed before treatment starts and monitored periodically thereafter, and DoctorOnCall’s online consultation process ensures these checks are in place before the prescription is confirmed or renewed.
Frequently Asked Questions
No. Glucophage XR 1000mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Glucophage XR 1000mg Tablet is a tablet containing Metformin Hydrochloride 1000mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in pack sizes of 60s-x3, 10s and 60s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store below 30°C in a dry place, protected from direct light and humidity, and keep tablets in their original blister packaging until needed. Keep out of the sight and reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Glucophage XR 1000mg Tablet is generally stable until the expiry date printed on the blister or carton when stored under the recommended conditions. Do not use tablets beyond the printed expiry date.
Good service. Fast reply. Fast delivery. Good product quality. Good value for money. Excellent service by seller. Trusted and recommended seller. Terima kasih
Verified purchase
Ng Chee Weng · Purchased: 60s x3
Legit product. Good quality still like old time. Value for money. Fast delivery too.
Verified purchase
Nur Izzah · Purchased: 60s
The seller shipped it very quickly and provided good service. I give a thumbs up to the boss and will buy from him next time!
Verified purchase
S. Karthik · Purchased: 60s
Harga murah dari kedai luar terbaik boleh repeat lagi nanti ok
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Important Medical Information
💊 Recommended Dosage:
The dose of Glucophage XR 1000mg Tablet is individualised by the prescribing doctor, typically as part of a gradual increase from a lower XR strength based on blood glucose control and tolerability. Because it is an extended-release formulation, the total daily dose is generally taken as a single dose with the evening meal rather than split across the day, and any change should only be made by the doctor after reviewing blood glucose readings and kidney function.
🛑 Contraindications (Do not use if):
Known hypersensitivity to metformin
Moderate to severe kidney impairment, as assessed by the prescribing doctor
Acute conditions with risk of altered kidney function, such as severe dehydration, serious infection, or shock
Unstable or acute decompensated heart failure
Conditions predisposing to tissue hypoxia, such as acute heart attack or severe respiratory failure
Planned use of iodinated contrast dye for imaging, unless timed by the doctor around the procedure
Any condition causing significant narrowing of the gastrointestinal tract, which may affect passage of the tablet matrix
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
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IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.