Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Glucophage XR 750mg Tablet is supplied as a tablet, with Metformin HCl (extended-release) 750mg. It is supplied in pack sizes of 15s and 60s.
No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.
If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.
Directions for Use
Take Glucophage XR 750mg Tablet exactly as prescribed by your doctor, usually once daily with the evening meal unless advised otherwise. Swallow the tablet whole with a glass of water — do not crush, chew, or split it, as this can affect the extended-release mechanism and how the medicine is absorbed. Do not stop or change the dose without first consulting your doctor, even if you feel your blood glucose is well controlled.
Dosage
Dosage of Glucophage XR 750mg Tablet is individualised by the prescribing doctor based on blood glucose readings, kidney function, and response to treatment, and may be adjusted gradually to the lowest effective dose. This medicine requires a valid doctor’s prescription and should never be started, stopped, or adjusted without medical advice, as inappropriate dosing can affect blood glucose control or increase the risk of side effects, particularly in patients with reduced kidney function.
Shelf Life
Glucophage XR 750mg Tablet is generally stable for the shelf life stated on the carton when stored correctly and unopened. Always check the expiry date printed on the packaging before use, and do not use the tablets after this date. Your pharmacist can confirm the exact expiry date on the specific pack dispensed to you.
Storage Instructions
Store Glucophage XR 750mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging until ready for use. Keep out of reach and sight of children. Do not store in the bathroom or near a sink, and do not use tablets that appear discoloured or damaged.
Side Effects
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Contraindications
Known hypersensitivity to metformin or any component of the tablet
Severe kidney impairment or acute kidney injury
Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Severe liver impairment
Conditions with risk of tissue hypoxia, such as recent heart attack, severe heart failure, or shock
Planned use of iodinated contrast media for imaging — treatment may need temporary interruption
Excessive alcohol intake
Drug / Food Interactions
Iodinated contrast agents used in radiological procedures may increase the risk of lactic acidosis and kidney impairment
Certain diuretics, corticosteroids, and other medicines that affect kidney function or blood glucose may alter metformin’s effect
Alcohol may increase the risk of lactic acidosis, especially with excessive intake
Other antidiabetic medicines may increase the risk of hypoglycaemia when combined
Inform your doctor or pharmacist of all prescription, over-the-counter, and herbal products you are taking
Quick Tips
Take with the evening meal to help reduce stomach upset
Swallow the tablet whole — never crush, chew, or split it
Attend regular follow-up appointments so your doctor can monitor blood glucose and kidney function
Inform your doctor if you are scheduled for any contrast imaging (such as a CT scan) or surgery
Watch for unusual muscle pain, breathing difficulty, or extreme tiredness and seek medical attention promptly if these occur
Do not double the dose if you miss one — continue with the next scheduled dose
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally Safe
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Glucophage XR 750mg Tablet is a prescription antidiabetic medicine and should only be used under ongoing medical supervision. Regular monitoring of blood glucose, HbA1c, and kidney function is important to ensure the medicine remains effective and safe. Patients should not share this medicine with others and should always consult their doctor or a DoctorOnCall pharmacist before making any changes to their diabetes treatment plan.
Frequently Asked Questions
No. Glucophage XR 750mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Glucophage XR 750mg Tablet is a tablet containing Metformin HCl (extended-release) 750mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in pack sizes of 15s and 60s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store Glucophage XR 750mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging until ready for use. Keep out of reach and sight of children. Do not store in the bathroom or near a sink, and do not use tablets that appear discoloured or damaged. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
What condition or symptom are you treating with this medication?
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Important Medical Information
💊 Recommended Dosage:
Dosage of Glucophage XR 750mg Tablet is individualised by the prescribing doctor based on blood glucose readings, kidney function, and response to treatment, and may be adjusted gradually to the lowest effective dose. This medicine requires a valid doctor’s prescription and should never be started, stopped, or adjusted without medical advice, as inappropriate dosing can affect blood glucose control or increase the risk of side effects, particularly in patients with reduced kidney function.
🛑 Contraindications (Do not use if):
Known hypersensitivity to metformin or any component of the tablet
Severe kidney impairment or acute kidney injury
Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Severe liver impairment
Conditions with risk of tissue hypoxia, such as recent heart attack, severe heart failure, or shock
Planned use of iodinated contrast media for imaging — treatment may need temporary interruption
Excessive alcohol intake
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.