Glucophage XR 750mg Tablet

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Overview

Glucophage XR 750mg Tablet is supplied as a tablet, with Metformin HCl (extended-release) 750mg. It is supplied in pack sizes of 15s and 60s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Take Glucophage XR 750mg Tablet exactly as prescribed by your doctor, usually once daily with the evening meal unless advised otherwise. Swallow the tablet whole with a glass of water — do not crush, chew, or split it, as this can affect the extended-release mechanism and how the medicine is absorbed. Do not stop or change the dose without first consulting your doctor, even if you feel your blood glucose is well controlled.

Dosage

Dosage of Glucophage XR 750mg Tablet is individualised by the prescribing doctor based on blood glucose readings, kidney function, and response to treatment, and may be adjusted gradually to the lowest effective dose. This medicine requires a valid doctor’s prescription and should never be started, stopped, or adjusted without medical advice, as inappropriate dosing can affect blood glucose control or increase the risk of side effects, particularly in patients with reduced kidney function.

Shelf Life

Glucophage XR 750mg Tablet is generally stable for the shelf life stated on the carton when stored correctly and unopened. Always check the expiry date printed on the packaging before use, and do not use the tablets after this date. Your pharmacist can confirm the exact expiry date on the specific pack dispensed to you.

Storage Instructions

Store Glucophage XR 750mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging until ready for use. Keep out of reach and sight of children. Do not store in the bathroom or near a sink, and do not use tablets that appear discoloured or damaged.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to metformin or any component of the tablet
  • Severe kidney impairment or acute kidney injury
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
  • Conditions with risk of tissue hypoxia, such as recent heart attack, severe heart failure, or shock
  • Planned use of iodinated contrast media for imaging — treatment may need temporary interruption
  • Excessive alcohol intake

Drug / Food Interactions

  • Iodinated contrast agents used in radiological procedures may increase the risk of lactic acidosis and kidney impairment
  • Certain diuretics, corticosteroids, and other medicines that affect kidney function or blood glucose may alter metformin’s effect
  • Alcohol may increase the risk of lactic acidosis, especially with excessive intake
  • Other antidiabetic medicines may increase the risk of hypoglycaemia when combined
  • Inform your doctor or pharmacist of all prescription, over-the-counter, and herbal products you are taking

Quick Tips

  • Take with the evening meal to help reduce stomach upset
  • Swallow the tablet whole — never crush, chew, or split it
  • Attend regular follow-up appointments so your doctor can monitor blood glucose and kidney function
  • Inform your doctor if you are scheduled for any contrast imaging (such as a CT scan) or surgery
  • Watch for unusual muscle pain, breathing difficulty, or extreme tiredness and seek medical attention promptly if these occur
  • Do not double the dose if you miss one — continue with the next scheduled dose

Frequently Asked Questions

Do I need a prescription to buy Glucophage XR 750mg Tablet?

No. Glucophage XR 750mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Glucophage XR 750mg Tablet contain?

Glucophage XR 750mg Tablet is a tablet containing Metformin HCl (extended-release) 750mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Glucophage XR 750mg Tablet come in?

It is supplied in pack sizes of 15s and 60s. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Glucophage XR 750mg Tablet is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Glucophage XR 750mg Tablet?

Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Glucophage XR 750mg Tablet before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

How should I store Glucophage XR 750mg Tablet?

Store Glucophage XR 750mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging until ready for use. Keep out of reach and sight of children. Do not store in the bathroom or near a sink, and do not use tablets that appear discoloured or damaged. Keep it in its original pack and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects after using Glucophage XR 750mg Tablet?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Glucophage XR 750mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Glucophage XR 750mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Metformin HCl (extended-release) 750mg (active ingredient)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Glucophage XR 750mg Tablet is a prescription antidiabetic medicine and should only be used under ongoing medical supervision. Regular monitoring of blood glucose, HbA1c, and kidney function is important to ensure the medicine remains effective and safe. Patients should not share this medicine with others and should always consult their doctor or a DoctorOnCall pharmacist before making any changes to their diabetes treatment plan.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

Dosage of Glucophage XR 750mg Tablet is individualised by the prescribing doctor based on blood glucose readings, kidney function, and response to treatment, and may be adjusted gradually to the lowest effective dose. This medicine requires a valid doctor’s prescription and should never be started, stopped, or adjusted without medical advice, as inappropriate dosing can affect blood glucose control or increase the risk of side effects, particularly in patients with reduced kidney function.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to metformin or any component of the tablet
  • Severe kidney impairment or acute kidney injury
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
  • Conditions with risk of tissue hypoxia, such as recent heart attack, severe heart failure, or shock
  • Planned use of iodinated contrast media for imaging — treatment may need temporary interruption
  • Excessive alcohol intake
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.