Glucophage XR 750mg Tablet

Brand Merck
Manufacturer Merck
  • Fast Delivery
  • Muslim-Friendly
  • FDA Approved
  • Secure Payment
Save: RM26.20   25% OFF
🎟️ Available Vouchers
DELIVERY5
RM5 OFF
Min Spend RM120.00
PAYDAY25
RM25 OFF
Min Spend RM500.00
Valid till: 3 Nov 2026
PAYDAY10
RM10 OFF
Min Spend RM200.00
Valid till: 3 Nov 2026

Click a voucher to copy the code. Automatically applied at checkout if conditions are met.

Have questions? Chat with us on WhatsApp
Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Glucophage XR 750mg Tablet is supplied as a tablet, with Metformin HCl (extended-release) 750mg. It is supplied in pack sizes of 15s and 60s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Take Glucophage XR 750mg Tablet exactly as prescribed by your doctor, usually once daily with the evening meal unless advised otherwise. Swallow the tablet whole with a glass of water — do not crush, chew, or split it, as this can affect the extended-release mechanism and how the medicine is absorbed. Do not stop or change the dose without first consulting your doctor, even if you feel your blood glucose is well controlled.

Dosage

Dosage of Glucophage XR 750mg Tablet is individualised by the prescribing doctor based on blood glucose readings, kidney function, and response to treatment, and may be adjusted gradually to the lowest effective dose. This medicine requires a valid doctor’s prescription and should never be started, stopped, or adjusted without medical advice, as inappropriate dosing can affect blood glucose control or increase the risk of side effects, particularly in patients with reduced kidney function.

Shelf Life

Glucophage XR 750mg Tablet is generally stable for the shelf life stated on the carton when stored correctly and unopened. Always check the expiry date printed on the packaging before use, and do not use the tablets after this date. Your pharmacist can confirm the exact expiry date on the specific pack dispensed to you.

Storage Instructions

Store Glucophage XR 750mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, in its original packaging until ready for use. Keep out of reach and sight of children. Do not store in the bathroom or near a sink, and do not use tablets that appear discoloured or damaged.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to metformin or any component of the tablet
  • Severe kidney impairment or acute kidney injury
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
  • Conditions with risk of tissue hypoxia, such as recent heart attack, severe heart failure, or shock
  • Planned use of iodinated contrast media for imaging — treatment may need temporary interruption
  • Excessive alcohol intake

Drug / Food Interactions

  • Iodinated contrast agents used in radiological procedures may increase the risk of lactic acidosis and kidney impairment
  • Certain diuretics, corticosteroids, and other medicines that affect kidney function or blood glucose may alter metformin’s effect
  • Alcohol may increase the risk of lactic acidosis, especially with excessive intake
  • Other antidiabetic medicines may increase the risk of hypoglycaemia when combined
  • Inform your doctor or pharmacist of all prescription, over-the-counter, and herbal products you are taking

Quick Tips

  • Take with the evening meal to help reduce stomach upset
  • Swallow the tablet whole — never crush, chew, or split it
  • Attend regular follow-up appointments so your doctor can monitor blood glucose and kidney function
  • Inform your doctor if you are scheduled for any contrast imaging (such as a CT scan) or surgery
  • Watch for unusual muscle pain, breathing difficulty, or extreme tiredness and seek medical attention promptly if these occur
  • Do not double the dose if you miss one — continue with the next scheduled dose

Ingredients / Active Ingredients

  • Metformin HCl (extended-release) 750mg (active ingredient)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Glucophage XR 750mg Tablet is a prescription antidiabetic medicine and should only be used under ongoing medical supervision. Regular monitoring of blood glucose, HbA1c, and kidney function is important to ensure the medicine remains effective and safe. Patients should not share this medicine with others and should always consult their doctor or a DoctorOnCall pharmacist before making any changes to their diabetes treatment plan.

Frequently Asked Questions

Product Specifications

BrandMerck
ManufacturerMerck
ClassificationNon-prescription
Ingredients / Active IngredientsMetformin
Pack Size15s, 60s

Customer Reviews

Be the first to review this product.

Confirm Action
×

Are you sure?

Mixed cart not supported

×

We currently don't support mixed carts. Subscription items and normal items have to be checked out separately.

×

Pharmacist Screening

×

What condition or symptom are you treating with this medication?

*Please select the closest match. A pharmacist may call to verify your selection before dispensing.

Important Medical Information

💊 Recommended Dosage:

Dosage of Glucophage XR 750mg Tablet is individualised by the prescribing doctor based on blood glucose readings, kidney function, and response to treatment, and may be adjusted gradually to the lowest effective dose. This medicine requires a valid doctor’s prescription and should never be started, stopped, or adjusted without medical advice, as inappropriate dosing can affect blood glucose control or increase the risk of side effects, particularly in patients with reduced kidney function.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to metformin or any component of the tablet
  • Severe kidney impairment or acute kidney injury
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
  • Conditions with risk of tissue hypoxia, such as recent heart attack, severe heart failure, or shock
  • Planned use of iodinated contrast media for imaging — treatment may need temporary interruption
  • Excessive alcohol intake
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.