Pharmaniaga Glumet XR 750mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Pharmaniaga Glumet XR 750mg Tablet is supplied as a tablet, with Metformin hydrochloride 750mg per tablet, in extended-release form. It is supplied in a pack size of 10s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Take Glumet XR 750mg Tablet exactly as prescribed by your doctor, usually once daily with the evening meal. Swallow the tablet whole with a glass of water; do not crush, split, or chew it, as breaking the tablet can disrupt the extended-release matrix and increase the risk of side effects. If you are switching from another metformin product, your doctor will advise the correct starting dose and timing for the change. Do not stop or adjust your dose on your own, even if your blood glucose readings appear normal, as this can affect long-term diabetes control.

Dosage

The dose of Glumet XR 750mg Tablet is individualised by your prescribing doctor based on your blood glucose control, kidney function, and response to treatment, and should never be self-adjusted. Treatment is often started at a lower dose and increased gradually over several weeks to reduce gastrointestinal side effects, with your doctor confirming the appropriate maintenance dose at follow-up visits. Regular monitoring of blood glucose, HbA1c, and kidney function is required while you are taking this medicine. If a dose is missed, take it as soon as you remember unless it is close to the time of your next dose; do not take a double dose to make up for the one missed.

Storage Instructions

Store Glumet XR 750mg Tablet below 30°C in a dry place, away from direct sunlight and moisture, and keep it out of the reach of children. Keep tablets in their original blister packaging until you are ready to take them.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to metformin or any ingredient in the tablet.
  • Severe kidney impairment.
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
  • Severe liver impairment.
  • Conditions associated with tissue hypoxia, such as recent heart attack, severe heart failure, or shock.
  • Acute conditions with risk of altered kidney function, such as severe dehydration or serious infection.

Drug / Food Interactions

  • Iodinated contrast media used in imaging studies may increase the risk of lactic acidosis; metformin may need to be paused before and after such procedures.
  • Alcohol can increase the risk of lactic acidosis and low blood sugar when taken with metformin.
  • Certain diuretics, corticosteroids, and some blood pressure medicines may affect blood glucose control.
  • Other diabetes medicines, including insulin and sulfonylureas, may increase the risk of hypoglycaemia when combined with metformin.
  • Cimetidine may increase metformin blood levels.

Quick Tips

  • Take Glumet XR with your evening meal to reduce stomach upset.
  • Swallow the tablet whole — never crush, split, or chew it.
  • Attend all scheduled blood tests to monitor kidney function and vitamin B12 levels.
  • Continue your prescribed diet and exercise plan alongside this medicine.
  • Inform your doctor before any surgery or contrast imaging scan.
  • Carry a note stating you are on metformin therapy, especially when travelling.

Ingredients / Active Ingredients

  • Active ingredient: Metformin hydrochloride 750mg per tablet, in extended-release form.
  • Formulated as a modified-release matrix tablet for once-daily dosing.
  • Manufactured by Pharmaniaga Berhad.
  • Full list of inactive/excipient ingredients is available on the product package insert.

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Precautions: Glumet XR 750mg Tablet should be used with caution in elderly patients, people with reduced kidney function, and those who consume alcohol regularly, as these factors increase the risk of lactic acidosis. It is not recommended during pregnancy or breastfeeding unless specifically advised by a doctor, and is not intended for children.

When to See a Doctor or Pharmacist: Seek prompt medical advice if you experience persistent vomiting, severe abdominal pain, difficulty breathing, unusual muscle pain, or unusually low body temperature, as these may indicate lactic acidosis. Contact DoctorOnCall’s pharmacist team if you have questions about your dose, a missed dose, or possible side effects.

Frequently Asked Questions

Product Specifications

BrandPharmaniaga
ClassificationNon-prescription
Ingredients / Active IngredientsMetformin
Pack Size10s
Shelf LifePlease refer to the expiry date printed on the blister strip or carton, and do not use Glumet XR 750mg Tablet beyond this date.

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Important Medical Information

💊 Recommended Dosage:

The dose of Glumet XR 750mg Tablet is individualised by your prescribing doctor based on your blood glucose control, kidney function, and response to treatment, and should never be self-adjusted. Treatment is often started at a lower dose and increased gradually over several weeks to reduce gastrointestinal side effects, with your doctor confirming the appropriate maintenance dose at follow-up visits. Regular monitoring of blood glucose, HbA1c, and kidney function is required while you are taking this medicine. If a dose is missed, take it as soon as you remember unless it is close to the time of your next dose; do not take a double dose to make up for the one missed.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to metformin or any ingredient in the tablet.
  • Severe kidney impairment.
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
  • Severe liver impairment.
  • Conditions associated with tissue hypoxia, such as recent heart attack, severe heart failure, or shock.
  • Acute conditions with risk of altered kidney function, such as severe dehydration or serious infection.
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.