Proezine 25mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Proezine 25mg Tablet is supplied as a tablet, with Promethazine hydrochloride 25mg. It is supplied in a pack size of 10s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Take Proezine 25mg Tablet exactly as prescribed by your doctor, usually swallowed whole with water. For allergic conditions it may be taken at night due to its sedating effect, while for motion sickness it is generally taken before travel begins, as directed. Avoid driving or operating machinery until you know how this tablet affects you, as it can cause marked drowsiness.

Dosage

The dose and frequency of Proezine 25mg Tablet are determined by your doctor based on the condition being treated, your age, and your response to treatment, with adults typically taking one tablet at a time and not exceeding the maximum daily dose set by your doctor. Do not increase the dose or frequency on your own even if symptoms persist.

Storage Instructions

Store Proezine 25mg Tablet below 30°C in a dry place, protected from light and moisture, and keep it out of the reach of children.

Side Effects

  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children

Contraindications

  • Children under 2 years old, due to the risk of severe respiratory depression
  • Severe central nervous system depression or coma
  • Narrow-angle glaucoma
  • Severe liver disease
  • Known hypersensitivity to promethazine or other phenothiazines
  • Concurrent use with other strong CNS depressants without medical supervision

Drug / Food Interactions

  • Alcohol and other sedating medicines increase the risk of excessive drowsiness and respiratory depression
  • Monoamine oxidase inhibitors (MAOIs) can prolong and intensify the sedative and anticholinergic effects
  • Other anticholinergic medicines may increase dry mouth, constipation, and urinary retention
  • May mask signs of ototoxicity from other medicines
  • Central nervous system depressants such as opioids, benzodiazepines, and sleep aids increase sedation risk

Quick Tips

  • Take Proezine 25mg Tablet at night where possible if drowsiness is a concern during the day
  • Avoid alcohol while taking this medicine
  • Do not drive or operate machinery until you know how the tablet affects you
  • Keep well hydrated and inform your doctor if you have difficulty urinating
  • Do not give this medicine to young children without explicit medical advice

Ingredients / Active Ingredients

  • Promethazine hydrochloride 25mg
  • Lactose monohydrate
  • Maize starch
  • Magnesium stearate
  • Talc
  • Colouring agents

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Promethazine’s sedating effects can be more pronounced in elderly patients and those with existing respiratory or liver conditions, so DoctorOnCall’s doctors will review your full medical history before prescribing Proezine 25mg Tablet, and may recommend against use in certain age groups or alongside specific other medicines.

Frequently Asked Questions

Product Specifications

BrandDuopharma
ClassificationNon-prescription
Ingredients / Active IngredientsPromethazine
Pack Size10s
Shelf LifeProezine 25mg Tablet remains stable until the expiry date printed on the packaging when stored under recommended conditions and left unopened. Do not use the tablets after the expiry date.

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Important Medical Information

💊 Recommended Dosage:

The dose and frequency of Proezine 25mg Tablet are determined by your doctor based on the condition being treated, your age, and your response to treatment, with adults typically taking one tablet at a time and not exceeding the maximum daily dose set by your doctor. Do not increase the dose or frequency on your own even if symptoms persist.

🛑 Contraindications (Do not use if):
  • Children under 2 years old, due to the risk of severe respiratory depression
  • Severe central nervous system depression or coma
  • Narrow-angle glaucoma
  • Severe liver disease
  • Known hypersensitivity to promethazine or other phenothiazines
  • Concurrent use with other strong CNS depressants without medical supervision
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.