Xepagan 10mg/5ml Elixir

Brand Xepa
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Xepagan 10mg/5ml Elixir is supplied as a healthcare product, with Promethazine hydrochloride, equivalent to 10mg per 5ml of elixir. It is supplied in a pack size of 60ml.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Xepagan Elixir is taken by mouth, using the measuring cup or spoon supplied with the pack, generally at night or before an activity where drowsiness will not be a problem, since it can cause significant sedation. Shake the bottle well before use, and avoid combining it with other sedating cough/cold products or alcohol, as this can increase drowsiness and the risk of breathing difficulty.

Dosage

Dosing depends on age and body weight and should follow the product label or a pharmacist’s advice; typical adult dosing is in the range of 5-10ml (10-20mg) at night or as directed, while dosing in children is age-based and generally lower. Xepagan must not be given to children under 2 years of age, and any use in young children should only be under a doctor’s or pharmacist’s specific guidance because of the risk of respiratory depression.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight, keep the bottle tightly closed, and store out of the sight and reach of children.

Side Effects

  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children

Contraindications

  • Known hypersensitivity to promethazine or other phenothiazine medicines
  • Children under 2 years of age
  • Comatose states or use together with large amounts of CNS depressants
  • Severe liver disease, unless a doctor advises otherwise

Drug / Food Interactions

  • Alcohol and other sedating medicines (sleeping tablets, other antihistamines, opioid painkillers) — increased sedation and risk of breathing difficulty
  • Other anticholinergic medicines — increased dry mouth, constipation, urinary retention
  • MAOI antidepressants — may intensify anticholinergic and sedative effects; seek medical advice if you are on this class of medicine

Quick Tips

  • Take at night or when drowsiness will not interfere with driving, work, or caring for children
  • Do not combine with alcohol or other sedating cough/cold medicines
  • Never give to a child under 2 years of age
  • Use only the measuring device provided for accurate dosing
  • Stay well hydrated, as promethazine can dry out the mouth and thicken mucus
  • Seek prompt medical attention if breathing becomes slow, shallow, or laboured after a dose

Ingredients / Active Ingredients

  • Active ingredient: Promethazine hydrochloride, equivalent to 10mg per 5ml of elixir
  • Drug class: first-generation (sedating) antihistamine, phenothiazine derivative
  • Dosage form: oral elixir
  • Inactive ingredients are not fully disclosed on the public label; ask your pharmacist if you have specific excipient allergies

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Precautions: Xepagan causes significant drowsiness — avoid driving, operating machinery, or other activities requiring alertness after taking it, and avoid alcohol. Use with caution in the elderly, in anyone with asthma or chronic lung disease (thickened secretions may worsen breathing), glaucoma, or urinary retention, and check with a doctor or pharmacist before use in pregnancy or breastfeeding.

When to See a Doctor or Pharmacist: Seek medical advice promptly if a child under 2 years has been given this medicine, if breathing becomes slow or shallow at any age, if excessive drowsiness or difficulty waking occurs, or if allergy symptoms or cough do not improve after a few days of use.

Frequently Asked Questions

Product Specifications

BrandXepa
ClassificationNon-prescription
Ingredients / Active IngredientsPromethazine
Volume60ml
Shelf LifeUse Xepagan Elixir before the expiry date printed on the bottle or carton, and do not use it beyond this date even if the elixir appears unchanged.

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Important Medical Information

💊 Recommended Dosage:

Dosing depends on age and body weight and should follow the product label or a pharmacist’s advice; typical adult dosing is in the range of 5-10ml (10-20mg) at night or as directed, while dosing in children is age-based and generally lower. Xepagan must not be given to children under 2 years of age, and any use in young children should only be under a doctor’s or pharmacist’s specific guidance because of the risk of respiratory depression.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to promethazine or other phenothiazine medicines
  • Children under 2 years of age
  • Comatose states or use together with large amounts of CNS depressants
  • Severe liver disease, unless a doctor advises otherwise
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.