Rhinathiol Promethazine Syrup

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Rhinathiol Promethazine Syrup is a syrup with Carbocisteine declared as its active content. It is supplied in a pack size of 125ml.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Shake the bottle well before each use, measure the dose using the measuring cup provided, and take with food or a meal to reduce the chance of stomach upset; because promethazine can cause drowsiness, avoid driving or operating machinery after taking a dose.

Dosage

Dosing is individualised based on age and the doctor’s prescription; adults are typically prescribed a measured dose taken two to three times daily, while dosing in children requires careful medical assessment and is not recommended in very young children due to the risk of serious breathing problems associated with promethazine.

Storage Instructions

Store below 30°C in a dry place, protected from light, with the cap tightly closed between uses, and keep well out of the reach of children.

Side Effects

  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children

Contraindications

  • Children under 2 years of age (risk of severe or fatal respiratory depression associated with promethazine)
  • Known hypersensitivity to phenothiazine-type medicines
  • Severe liver disease
  • Narrow-angle glaucoma
  • Epilepsy or seizure disorders (use with caution)
  • Concurrent use of other sedating medicines without medical advice

Drug / Food Interactions

  • Alcohol and other central nervous system depressants (sleeping tablets, some antidepressants, opioid painkillers) can significantly increase drowsiness and sedation
  • Monoamine oxidase inhibitors (MAOIs) may interact and should be discussed with a doctor
  • Other anticholinergic medicines may add to side effects such as dry mouth and blurred vision

Quick Tips

  • Take with food to reduce stomach upset
  • Avoid alcohol and other sedating medicines while using this syrup
  • Do not drive or operate machinery if you feel drowsy after a dose
  • Consider taking the evening dose closer to bedtime if drowsiness is helpful for a night-time cough
  • See a doctor if the cough persists beyond a week, worsens, or is accompanied by fever or breathing difficulty

Ingredients / Active Ingredients

  • Carbocisteine
  • Promethazine hydrochloride
  • Sucrose or sorbitol solution
  • Flavouring agent
  • Preservative
  • Purified water

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Because Rhinathiol Promethazine Syrup combines a sedating antihistamine with a mucolytic, doctor assessment before use helps ensure the correct dose for the patient’s age and confirms that the cough is not a symptom of a more serious underlying condition; medical follow-up is particularly important for children, the elderly, and anyone using other sedating medicines.

Frequently Asked Questions

Product Specifications

BrandSanofi-Aventis
ClassificationNon-prescription
Ingredients / Active IngredientsPromethazine
Volume125ml
Shelf LifeRhinathiol Promethazine Syrup is generally stable for around 2 years when unopened; once opened, use within the timeframe stated on the label and always check the expiry date before use.

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Important Medical Information

💊 Recommended Dosage:

Dosing is individualised based on age and the doctor’s prescription; adults are typically prescribed a measured dose taken two to three times daily, while dosing in children requires careful medical assessment and is not recommended in very young children due to the risk of serious breathing problems associated with promethazine.

🛑 Contraindications (Do not use if):
  • Children under 2 years of age (risk of severe or fatal respiratory depression associated with promethazine)
  • Known hypersensitivity to phenothiazine-type medicines
  • Severe liver disease
  • Narrow-angle glaucoma
  • Epilepsy or seizure disorders (use with caution)
  • Concurrent use of other sedating medicines without medical advice
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.