Upha Proezine 5mg Syrup

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Overview

Upha Proezine 5mg Syrup is supplied as a syrup, with Promethazine hydrochloride 5mg per 5mL dose. It is supplied in a pack size of 90ml.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Upha Proezine Syrup should only be given according to the exact dose and schedule confirmed by the prescribing doctor following an online consultation via DoctorOnCall. Use the measuring cup or oral syringe provided to measure the dose accurately, shake the bottle well before each use, and give with or after food to reduce the chance of stomach upset.

Dosage

Dosage is individualised by the prescribing doctor based on the patient’s age, body weight, and the condition being treated, and must not be adjusted without medical advice. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should not be given to infants below 2 years of age due to the risk of severe breathing problems.

Shelf Life

Upha Proezine 5mg Syrup is generally stable for up to 24 months from the date of manufacture when unopened and stored correctly; once opened, it should be used within the period stated on the label, typically a few weeks. Always check the expiry date on the bottle before use.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight, and keep the bottle tightly closed when not in use. Keep out of reach and sight of children, and do not use if the syrup shows signs of discolouration or unusual odour.

Side Effects

  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children

Contraindications

  • Children under 2 years of age, due to the risk of severe or fatal respiratory depression
  • Known hypersensitivity to promethazine or other phenothiazine medicines
  • Severe liver disease
  • Comatose states or severe central nervous system depression
  • Concurrent use with other strong sedating medicines unless directed by a doctor

Drug / Food Interactions

  • Increased sedation when combined with alcohol, sleeping tablets, opioids, or other sedating antihistamines
  • May increase the central nervous system depressant effects of anaesthetics and certain anti-anxiety medicines
  • Should not be combined with monoamine oxidase inhibitors (MAOIs)
  • May mask signs of ototoxicity when taken with certain antibiotics such as aminoglycosides
  • Anticholinergic effects may be increased when combined with other anticholinergic medicines

Quick Tips

  • Only use this syrup exactly as prescribed by your doctor following an online consultation via DoctorOnCall
  • Avoid driving, cycling, or operating machinery after taking this medicine due to sedation
  • Never give this medicine to infants below 2 years old
  • Keep follow-up appointments so your doctor can monitor response and adjust treatment if needed
  • Seek urgent medical attention if breathing becomes difficult or unusual drowsiness occurs, especially in a child

Frequently Asked Questions

Do I need a prescription to buy Upha Proezine 5mg Syrup?

No. Upha Proezine 5mg Syrup is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Upha Proezine 5mg Syrup contain?

Upha Proezine 5mg Syrup is a syrup containing Promethazine hydrochloride 5mg per 5mL dose. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Upha Proezine 5mg Syrup come in?

It is supplied in a pack size of 90ml. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Upha Proezine 5mg Syrup is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Upha Proezine 5mg Syrup?

Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Upha Proezine 5mg Syrup before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

How should I store Upha Proezine 5mg Syrup?

Store below 30°C in a cool, dry place away from direct sunlight, and keep the bottle tightly closed when not in use. Keep out of reach and sight of children, and do not use if the syrup shows signs of discolouration or unusual odour. Keep it in its original pack and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects after using Upha Proezine 5mg Syrup?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Upha Proezine 5mg Syrup be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Upha Proezine 5mg Syrup registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Promethazine hydrochloride 5mg per 5mL dose
  • Sucrose or sugar-based syrup base
  • Flavouring agent
  • Preservative
  • Purified water

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Limited Data

Limited data in kidney disease patients. Use only if necessary.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Promethazine-based syrups such as Upha Proezine are prescription-only in Malaysia and Singapore due to well-documented pediatric respiratory risks and significant sedative effects, and are dispensed only after a doctor has reviewed the patient’s suitability through an online consultation. Ongoing monitoring by a doctor or pharmacist is recommended, particularly in young children, the elderly, and patients taking other sedating medicines.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

Dosage is individualised by the prescribing doctor based on the patient’s age, body weight, and the condition being treated, and must not be adjusted without medical advice. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should not be given to infants below 2 years of age due to the risk of severe breathing problems.

🛑 Contraindications (Do not use if):
  • Children under 2 years of age, due to the risk of severe or fatal respiratory depression
  • Known hypersensitivity to promethazine or other phenothiazine medicines
  • Severe liver disease
  • Comatose states or severe central nervous system depression
  • Concurrent use with other strong sedating medicines unless directed by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Drowsiness or dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Skin sensitivity to sunlight
  • Confusion (especially in older adults)
  • Restlessness in children
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.