Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Upha Proezine 5mg Syrup is supplied as a syrup, with Promethazine hydrochloride 5mg per 5mL dose. It is supplied in a pack size of 90ml.
No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.
If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.
Directions for Use
Upha Proezine Syrup should only be given according to the exact dose and schedule confirmed by the prescribing doctor following an online consultation via DoctorOnCall. Use the measuring cup or oral syringe provided to measure the dose accurately, shake the bottle well before each use, and give with or after food to reduce the chance of stomach upset.
Dosage
Dosage is individualised by the prescribing doctor based on the patient’s age, body weight, and the condition being treated, and must not be adjusted without medical advice. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should not be given to infants below 2 years of age due to the risk of severe breathing problems.
Shelf Life
Upha Proezine 5mg Syrup is generally stable for up to 24 months from the date of manufacture when unopened and stored correctly; once opened, it should be used within the period stated on the label, typically a few weeks. Always check the expiry date on the bottle before use.
Storage Instructions
Store below 30°C in a cool, dry place away from direct sunlight, and keep the bottle tightly closed when not in use. Keep out of reach and sight of children, and do not use if the syrup shows signs of discolouration or unusual odour.
Side Effects
Drowsiness or dizziness
Dry mouth
Blurred vision
Constipation
Skin sensitivity to sunlight
Confusion (especially in older adults)
Restlessness in children
Contraindications
Children under 2 years of age, due to the risk of severe or fatal respiratory depression
Known hypersensitivity to promethazine or other phenothiazine medicines
Severe liver disease
Comatose states or severe central nervous system depression
Concurrent use with other strong sedating medicines unless directed by a doctor
Drug / Food Interactions
Increased sedation when combined with alcohol, sleeping tablets, opioids, or other sedating antihistamines
May increase the central nervous system depressant effects of anaesthetics and certain anti-anxiety medicines
Should not be combined with monoamine oxidase inhibitors (MAOIs)
May mask signs of ototoxicity when taken with certain antibiotics such as aminoglycosides
Anticholinergic effects may be increased when combined with other anticholinergic medicines
Quick Tips
Only use this syrup exactly as prescribed by your doctor following an online consultation via DoctorOnCall
Avoid driving, cycling, or operating machinery after taking this medicine due to sedation
Never give this medicine to infants below 2 years old
Keep follow-up appointments so your doctor can monitor response and adjust treatment if needed
Seek urgent medical attention if breathing becomes difficult or unusual drowsiness occurs, especially in a child
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Limited Data
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Limited Data
Limited data in kidney disease patients. Use only if necessary.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Not Advisable
It is not advisable to consume alcohol while taking this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Promethazine-based syrups such as Upha Proezine are prescription-only in Malaysia and Singapore due to well-documented pediatric respiratory risks and significant sedative effects, and are dispensed only after a doctor has reviewed the patient’s suitability through an online consultation. Ongoing monitoring by a doctor or pharmacist is recommended, particularly in young children, the elderly, and patients taking other sedating medicines.
Frequently Asked Questions
No. Upha Proezine 5mg Syrup is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Upha Proezine 5mg Syrup is a syrup containing Promethazine hydrochloride 5mg per 5mL dose. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 90ml. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store below 30°C in a cool, dry place away from direct sunlight, and keep the bottle tightly closed when not in use. Keep out of reach and sight of children, and do not use if the syrup shows signs of discolouration or unusual odour. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
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Important Medical Information
💊 Recommended Dosage:
Dosage is individualised by the prescribing doctor based on the patient’s age, body weight, and the condition being treated, and must not be adjusted without medical advice. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should not be given to infants below 2 years of age due to the risk of severe breathing problems.
🛑 Contraindications (Do not use if):
Children under 2 years of age, due to the risk of severe or fatal respiratory depression
Known hypersensitivity to promethazine or other phenothiazine medicines
Severe liver disease
Comatose states or severe central nervous system depression
Concurrent use with other strong sedating medicines unless directed by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Drowsiness or dizziness
Dry mouth
Blurred vision
Constipation
Skin sensitivity to sunlight
Confusion (especially in older adults)
Restlessness in children
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
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IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.