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H.pylori Infections and vonoprazan

Answered by: Dr Ramzdhan

Last Updated: June 5, 2020 1:07 AM

Anonymous 39 days

Hello doctor.
I am suffering from H.pylori and gastritis for 5 years. and used PPIs and Antibiotics many times but still have intensive inflation which distrupted my life truly and I am really worry it turns into dysplasia. Recently I have read about the efficacy of Vonoprazan compared to PPIs. Unfortunately doctors in my country dont have information about it and I need to order it online. I have some questions, would you please help me?
I have used 4 kinds of antibiotics before:

  1. Amoxiciline + Clarithromycine
  2. Amoxiciline + Metronidazole
  3. Amoxiciline + Levofloxacine
    but medicine in my country (Iran) usually have poor quality.
    I found a japanese website which provide vonoprazan with combination of Clarithromycine and Metronidazole. Since I used both of them before I dont know which package to choose? Is it possible that H.pylori shows less resistance to Japanese version of Clarithromycine or Metronidazole? Or should I take new antibiotics?
    another issue is that the price there was about $150 but its less expensive in your website. Is the quality different?

I read many medical papers during these 5 years.I had a boyfriend which was suspected to HIV. look likes there is a higher prevalence of H.pylori resistance in HIV/H.pylori co-infection patients. is there any hope this nasty bacteria eradicate completely? I am really worry and dont know what to do. Please help me :((((

Dr Ramzdhan 39 days
General Practitioner

Good evening to you too. Thank you for your question.

First and foremost, we truly understand your concerns regarding your symptoms. From your explanation, there are many possibilities that may lead to your ongoing problem.

  • bacterial resistance
  • inadequate treatment
  • misdiagnosed

After every treatment, the doctor should have recheck the effectiveness by identifying the existence of the bacterial to ensure full eradication. This can be done by various non invasive investigations. If the organism is not there and your symptoms still persist, there may be different factors that contribute to your symptoms sucj as stress, NSAIDs usage and many more.

As for the price, if the brand is the same, the quality is also the same. Price may differ due to company and products in malaysia is normally sell cheaper than abroad.

The solution to this problem is to identify the causes of bloated and treat the causes. However, this is just a general answer to your question. In order for us to provide you with an accurate choice of treatment and management, we need additional details to explore further into your current complaints. Therefore, we greatly suggest that you refer this to your nearest medical doctor. You may also click on this link (DoctorOnCall) to speak with our doctors online. We assure you that our conversations are kept in confidentiality unless additional consultation needed with other medical parties. Thank you.

Last Updated: Fri Jun 05 2020 01:07:45 GMT+0000 (Coordinated Universal Time)
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