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Spinal Muscular Atrophy (SMA)

Answered by: Dr Ramzdhan

Last Updated: June 22, 2021 9:57 AM
Anonymous 17 months

I want to marry a woman with two uncles have Spinal Muscular Atrophy (SMA). What is the possibilites that we have a children with this disease. PS: i dont have any family member with this disease.

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Dr Ramzdhan 17 months
General Practitioner

Hello and thank you for using our services

We understand that you want to marry someone with Spinal Muscular Atrophy and wants to know the possibilities and probability to pass it down to your children, is this correct? Don’t worry I will try to assist you with this matter.

Spinal muscular atrophy is a genetic disease characterized by weakness and wasting of muscle. If an individual with spinal muscular atrophy marries an individual without the disease or does not have the genetic for the disease, the child will be born as a carrier.

A carrier means he/she will carry the gene but will not be affected by the disease or develop any symptoms. Instead, carriers can pass down the gene to their children.

Spinal muscular atrophy can occur in a 25% chance when both parents are carriers or carry the gene.

If you have any other inquiries please let us know. You can contact our doctor via teleconsultation for more information.

Thank you.

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Last Updated: Tue Jun 22 2021 09:57:38 GMT+0800 (Malaysia Time)
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