Cavsamir 800mg Tablet

Introduction

Cavsamir is a film-coated tablet whose active ingredient is Sevelamer Carbonate (800 mg per tablet). It is a non-metal, non-calcium phosphate binder used in patients with chronic kidney disease (CKD) to reduce high levels of phosphate (hyperphosphatemia), especially in those on dialysis or in CKD not on dialysis when serum phosphorus is elevated.

Uses

• To control hyperphosphatemia (high blood phosphate) in adult patients receiving haemodialysis or peritoneal dialysis.
• To treat hyperphosphatemia in adult CKD patients not on dialysis when the serum phosphorus is ≥ 1.78 mmol/L.
• As part of a combined approach which may include dietary phosphorus restriction, calcium supplementation, active vitamin D (or analogues) to prevent renal bone disease.

Side Effects

Common / Very Common Side Effects: nausea, vomiting, diarrhea, constipation, abdominal pain, flatulence, indigestion.
Less Common / Serious Side Effects: gastrointestinal obstruction or perforation, severe constipation, hypersensitivity reactions (rash, itching), disturbances in fat-soluble vitamins (A, D, E, K) or folic acid levels with long-term use.

How to Use

• Take with meals, usually three times daily.
• Starting dose: 800-1600 mg per meal (1–2 tablets) three times daily, adjusted after about two weeks as needed.
• Swallow whole; do not chew, crush, or break the tablet.

Drug Interactions

Cavsamir may reduce absorption of other medicines.
Notable interactions: ciprofloxacin (take at least 2h before or 6h after), levothyroxine, mycophenolate mofetil, tacrolimus, cyclosporine.

How to Store

• Store at room temperature below 30°C.
• Keep container tightly closed, protect from moisture and light.
• Keep out of reach of children.
  

  FAQs

Q1: What happens if I miss a dose?
Take it with your next meal. If it’s close to your next dose, skip the missed one. Do not double dose.

Q2: Is it safe during pregnancy or breastfeeding?
Minimal absorption is expected, but use only if clearly needed and under medical advice.

Q3: Can I take Cavsamir if I have bowel disease or recent GI surgery?
Use with caution or avoid; risk of obstruction is higher.

Q4: Will it affect my vitamins?
Long-term use may lower fat-soluble vitamins and folic acid; supplements may be needed.

Q5: How quickly does it work?
Phosphate levels usually improve within 1–2 weeks, with dose adjustments as needed.

Q6: What if I have kidney impairment?
Cavsamir is indicated for CKD patients with high phosphate; however, other health conditions must be assessed by your doctor